DESMOID TUMOR
Clinical trials for DESMOID TUMOR explained in plain language.
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New hope for desmoid tumors: experimental drug ES014 enters phase 2 trial
Disease control Recruiting nowThis study tests an experimental drug called ES014 in 50 adults with desmoid tumors, a type of non-cancerous but often painful growth. The goal is to see if the drug can shrink or control the tumors and improve symptoms. Participants must have tumors that are growing or causing p…
Matched conditions: DESMOID TUMOR
Phase: PHASE2 • Sponsor: Elpiscience (Suzhou) Biopharma, Ltd. • Aim: Disease control
Last updated May 26, 2026 11:23 UTC
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New combo therapy freezes out desmoid tumors
Disease control Recruiting nowThis study tests a two-step treatment for desmoid tumors, which are non-cancerous growths that can cause pain and limit movement. First, participants take a daily oral drug called nirogacestat. Then, a single freezing procedure (cryoablation) is used to destroy the tumor. The goa…
Matched conditions: DESMOID TUMOR
Phase: PHASE2 • Sponsor: Nam Bui • Aim: Disease control
Last updated May 26, 2026 11:14 UTC
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New drug trial aims to protect fertility in women with rare tumors
Disease control Recruiting nowThis study tests a drug called nirogacestat in 50 premenopausal women with desmoid tumors (a type of non-cancerous growth). The main goal is to see how the drug affects ovarian function, such as menstrual periods and hormone levels. Participants will take the drug and be monitore…
Matched conditions: DESMOID TUMOR
Phase: PHASE4 • Sponsor: SpringWorks Therapeutics, Inc., a healthcare company of Merck KGaA, Darmstadt, Germany • Aim: Disease control
Last updated May 22, 2026 14:03 UTC
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Last-Resort drug access for rare tumor patients
Disease control AVAILABLEThis program provides nirogacestat to individual patients with serious desmoid tumors or NOTCH gene mutation positive tumors who have no other treatment options and cannot join a clinical trial. The goal is to control the disease when standard therapies have failed. Approval is n…
Matched conditions: DESMOID TUMOR
Sponsor: SpringWorks Therapeutics, Inc., a healthcare company of Merck KGaA, Darmstadt, Germany • Aim: Disease control
Last updated May 18, 2026 12:13 UTC
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Freezing tumors: a new hope for desmoid patients?
Disease control Recruiting nowThis study tests if freezing desmoid tumors (cryoablation) works better than standard medications for people whose tumors have grown after initial monitoring. About 150 participants aged 13 and older will be randomly assigned to one of the two treatments. The goal is to stop tumo…
Matched conditions: DESMOID TUMOR
Phase: NA • Sponsor: University Hospital, Strasbourg, France • Aim: Disease control
Last updated May 11, 2026 20:38 UTC