New combo therapy freezes out desmoid tumors
NCT ID NCT05949099
First seen Sep 30, 2025 · Last updated May 23, 2026 · Updated 36 times
Summary
This study tests a two-step treatment for desmoid tumors, which are non-cancerous growths that can cause pain and limit movement. First, participants take a daily oral drug called nirogacestat. Then, a single freezing procedure (cryoablation) is used to destroy the tumor. The goal is to see if this combination can stop the tumor from growing or shrink it for at least a year. About 28 adults with progressing or symptomatic tumors will take part.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Stanford University
RECRUITINGPalo Alto, California, 94395, United States
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Conditions
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