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New pill for advanced cancers enters early human testing

NCT ID NCT03264664

First seen Mar 18, 2026 · Last updated May 24, 2026 · Updated 14 times

Summary

This early-stage study tests an experimental drug called E7386 in about 60 adults with advanced or recurrent cancers that have no standard treatment options. The main goals are to check the drug's safety, find the best dose, and see if it can shrink tumors. Participants take the drug by mouth, and researchers monitor side effects and tumor response.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • California Liver Research Institute

    Pasadena, California, 91105, United States

  • Imperial College Healthcare NHS Trust

    London, W2 1NY, United Kingdom

  • Mayo Clinic Comprehensive Cancer

    Jacksonville, Florida, 32224, United States

  • Mayo Clinic Comprehensive Caner

    Phoenix, Arizona, 85054, United States

  • Mayo Clinic Comprehensive Caner

    Rochester, Minnesota, 55905, United States

  • Royal Free London NHS Foundation Trust, Royal Free Hospital

    London, NW3 2QG, United Kingdom

  • Royal Marsden Hospital NHS Foundation Trust

    Sutton, Surrey, SM2 5PT, United Kingdom

  • The Beatson West of Scotland Cancer Centre

    Glasgow, Lanarkshire, G12 0YN, United Kingdom

  • The Christie NHS Foundation Trust

    Manchester, Lancashire, M20 4BX, United Kingdom

  • USC Norris Comprehensive Cancer Center

    Los Angeles, California, 90033, United States

Conditions

Explore the condition pages connected to this study.