DESMOID TUMOR
Clinical trials for DESMOID TUMOR explained in plain language.
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New drug tested for rare tumors in young women
Disease control Recruiting nowThis study tests the drug nirogacestat in 50 premenopausal women (ages 18-40) with desmoid tumors, a rare type of non-cancerous growth. The main goal is to see how the drug affects ovarian function and to monitor any side effects. Participants will take the drug and be followed f…
Matched conditions: DESMOID TUMOR
Phase: PHASE4 • Sponsor: SpringWorks Therapeutics, Inc., a healthcare company of Merck KGaA, Darmstadt, Germany • Aim: Disease control
Last updated May 17, 2026 03:00 UTC
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Last-Resort drug access for rare tumor patients
Disease control AVAILABLEThis program provides nirogacestat to individual patients with serious desmoid tumors or NOTCH gene mutation positive tumors who have no other treatment options and cannot join a clinical trial. The goal is to control the disease when standard therapies have failed. Approval is n…
Matched conditions: DESMOID TUMOR
Sponsor: SpringWorks Therapeutics, Inc., a healthcare company of Merck KGaA, Darmstadt, Germany • Aim: Disease control
Last updated May 17, 2026 02:58 UTC
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New hope for rare tumor patients: ES014 drug trial launches
Disease control Recruiting nowThis study tests a new drug called ES014 in 50 adults with desmoid tumors, a rare type of growth that can cause pain and other problems. The goal is to see if ES014 can shrink or control the tumors and improve quality of life. Participants must have tumors that are growing or cau…
Matched conditions: DESMOID TUMOR
Phase: PHASE2 • Sponsor: Elpiscience (Suzhou) Biopharma, Ltd. • Aim: Disease control
Last updated May 15, 2026 11:54 UTC
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Freeze-and-Pill combo takes on rare tumors
Disease control Recruiting nowThis study tests a two-step approach for desmoid tumors, which are non-cancerous growths that can cause pain and limit movement. First, participants take a daily pill called nirogacestat, then doctors freeze the tumor using a procedure called cryoablation. The goal is to see if t…
Matched conditions: DESMOID TUMOR
Phase: PHASE2 • Sponsor: Nam Bui • Aim: Disease control
Last updated May 11, 2026 20:38 UTC
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Freezing tumors: a new hope for desmoid patients?
Disease control Recruiting nowThis study tests if freezing desmoid tumors (cryoablation) works better than standard medications for people whose tumors have grown after initial monitoring. About 150 participants aged 13 and older will be randomly assigned to one of the two treatments. The goal is to stop tumo…
Matched conditions: DESMOID TUMOR
Phase: NA • Sponsor: University Hospital, Strasbourg, France • Aim: Disease control
Last updated May 11, 2026 20:38 UTC