DESMOID TUMOR
Clinical trials for DESMOID TUMOR explained in plain language.
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New drug tested to protect fertility in women with rare tumors
Disease control Recruiting nowThis study tests the drug nirogacestat in 50 premenopausal women with desmoid tumors (a type of non-cancerous but aggressive growth). The main goal is to see if the drug affects ovarian function, such as menstrual periods and hormone levels. Participants take nirogacestat orally,…
Matched conditions: DESMOID TUMOR
Phase: PHASE4 • Sponsor: SpringWorks Therapeutics, Inc., a healthcare company of Merck KGaA, Darmstadt, Germany • Aim: Disease control
Last updated Jun 27, 2026 14:01 UTC
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New drug trial aims to shrink desmoid tumors
Disease control Recruiting nowThis study tests an investigational drug called nirogacestat in about 40 adults with desmoid tumors (a type of non-cancerous growth). The main goal is to check the drug's safety and side effects. Researchers will also see how the tumor responds to treatment.
Matched conditions: DESMOID TUMOR
Phase: PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Jun 27, 2026 12:32 UTC
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Last-Resort drug access for rare tumor patients
Disease control AVAILABLEThis program provides nirogacestat to people with serious desmoid tumors or NOTCH gene mutation tumors who have no other treatment options and cannot join a clinical trial. Each case is reviewed individually by the company, ethics board, and health authorities. The goal is to con…
Matched conditions: DESMOID TUMOR
Sponsor: SpringWorks Therapeutics, Inc., a healthcare company of Merck KGaA, Darmstadt, Germany • Aim: Disease control
Last updated Jun 27, 2026 12:30 UTC
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New drug ES014 targets desmoid tumors in Mid-Stage trial
Disease control Recruiting nowThis Phase 2 trial is testing a drug called ES014 in 50 adults with desmoid tumors, a type of non-cancerous but often painful growth. The drug is given as an IV infusion every two weeks. The main goal is to see if the tumors shrink, while also checking safety and quality of life.
Matched conditions: DESMOID TUMOR
Phase: PHASE2 • Sponsor: Elpiscience (Suzhou) Biopharma, Ltd. • Aim: Disease control
Last updated Jun 27, 2026 12:26 UTC
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New pill shows promise in slowing rare Cancer's growth
Disease control Recruiting nowThis study tests an experimental oral drug called cirtuvivint for people with advanced soft-tissue sarcoma that has not responded to prior treatment. About 25 participants in Spain will take the drug to see if it can stop or slow cancer growth for at least 3 months. The drug targ…
Matched conditions: DESMOID TUMOR
Phase: PHASE2 • Sponsor: Asociación Europea y Latinoamericana SELNET para la Investigación en Sarcomas • Aim: Disease control
Last updated Jun 27, 2026 12:04 UTC
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Freeze or chemo? new trial tests a less harsh option for desmoid tumors
Disease control Recruiting nowThis study tests whether freezing desmoid tumors with a needle (cryoablation) works better than standard chemotherapy for people whose tumors have grown after a period of watchful waiting. About 150 participants will be randomly assigned to one of the two treatments. If the tumor…
Matched conditions: DESMOID TUMOR
Phase: NA • Sponsor: University Hospital, Strasbourg, France • Aim: Disease control
Last updated Jun 27, 2026 07:57 UTC
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Freeze and pill combo takes on rare tumors
Disease control Recruiting nowThis study tests a two-step approach for desmoid tumors, which are non-cancerous but can be painful and grow. First, patients take a daily pill called nirogacestat for three months. Then, one tumor is frozen with a special needle (cryoablation). The goal is to see if this combina…
Matched conditions: DESMOID TUMOR
Phase: PHASE2 • Sponsor: Nam Bui • Aim: Disease control
Last updated Jun 26, 2026 14:56 UTC