CRITICALLY ILL
Clinical trials for CRITICALLY ILL explained in plain language.
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Vitamin d trial aims to shield kidneys in critical care
Prevention CompletedThis study tested whether two forms of activated vitamin D (calcifediol and calcitriol) could prevent or lessen acute kidney injury in critically ill patients. Researchers enrolled 150 adults in the ICU who were at high risk for kidney damage. The goal was to see if these vitamin…
Matched conditions: CRITICALLY ILL
Phase: PHASE2 • Sponsor: David Leaf • Aim: Prevention
Last updated May 22, 2026 14:01 UTC
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Breath test may predict ventilator weaning failure
Knowledge-focused CompletedThis study looked at 120 critically ill patients on breathing machines to see if a quick, non-invasive test called P0.1 could predict whether they would need the tube reinserted after removal. The test measures the effort to breathe in the first split second of an attempt. Resear…
Matched conditions: CRITICALLY ILL
Sponsor: Cleveland Clinic Abu Dhabi • Aim: Knowledge-focused
Last updated May 26, 2026 07:54 UTC
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ICU breathing tube study: does a simple wire tool boost First-Try success?
Knowledge-focused CompletedThis study looked at whether using a bendable wire (stylet) inside the breathing tube helps doctors place the tube correctly on the first try in critically ill patients. Over 1000 adults in intensive care who needed emergency breathing support took part. The goal was to see if th…
Matched conditions: CRITICALLY ILL
Phase: NA • Sponsor: University Hospital, Montpellier • Aim: Knowledge-focused
Last updated May 26, 2026 07:52 UTC
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Anemia duration linked to ventilator days in ICU patients
Knowledge-focused CompletedThis study looked at 236 adults in the surgical intensive care unit who needed a breathing machine for more than 4 days. Researchers wanted to see if the length of time a patient had anemia (low red blood cells) was related to how long they stayed on the ventilator. The goal was …
Matched conditions: CRITICALLY ILL
Sponsor: Mahidol University • Aim: Knowledge-focused
Last updated May 26, 2026 07:50 UTC
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Protein boost for sick kids: pilot study tests faster recovery
Knowledge-focused CompletedThis small pilot study looked at whether giving extra protein to underweight children in intensive care could help them leave the hospital sooner. The study enrolled 34 children and focused on whether the approach was practical, not on proving it works. The goal is to use these r…
Matched conditions: CRITICALLY ILL
Phase: NA • Sponsor: KK Women's and Children's Hospital • Aim: Knowledge-focused
Last updated May 26, 2026 07:49 UTC
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Speedy pneumonia test aims to get antibiotics right in the ICU
Knowledge-focused CompletedThis study tested a rapid test (BioFire FA Pneumonia Panel) to quickly find the germ causing pneumonia in ICU patients on breathing machines. 40 adults were randomly assigned to get the rapid test or usual care. The goal was to see if the test helps doctors choose the right antib…
Matched conditions: CRITICALLY ILL
Phase: PHASE2 • Sponsor: Chinese University of Hong Kong • Aim: Knowledge-focused
Last updated May 26, 2026 07:48 UTC
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French ICU study tracks COVID-19 care in over 1,000 patients
Knowledge-focused CompletedThis study looked at over 1,000 adults with COVID-19 who were admitted to intensive care units (ICUs) in France. Researchers collected information on how these patients were treated and what complications they had. The goal was to better understand what factors affect their recov…
Matched conditions: CRITICALLY ILL
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 26, 2026 07:23 UTC
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Can steady cuff pressure stop hidden lung infections in ICU patients?
Knowledge-focused CompletedThis study looked at whether keeping steady pressure on the breathing tube's cuff (the balloon that seals the airway) can reduce stomach fluid from leaking into the windpipe in critically ill patients. Researchers measured a stomach enzyme in lung fluids from 122 adults on breath…
Matched conditions: CRITICALLY ILL
Phase: PHASE4 • Sponsor: University Hospital, Lille • Aim: Knowledge-focused
Last updated May 18, 2026 12:01 UTC
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Global experts unite to clear the air on ICU breathing tube care
Knowledge-focused CompletedThis study brought together 35 healthcare experts from around the world to agree on the best methods for clearing mucus from the airways of critically ill patients who are on breathing machines. The goal was to create clear, practical guidelines for treatments like humidification…
Matched conditions: CRITICALLY ILL
Sponsor: Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) • Aim: Knowledge-focused
Last updated May 13, 2026 16:02 UTC
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Doctors test better way to measure kidney health in critically ill patients
Knowledge-focused CompletedThis study compared two different methods for measuring kidney function in critically ill ICU patients whose kidneys work unusually fast. Researchers tested 90 ICU patients to see if a newer test using a special dye (iohexol) gives more accurate results than the standard creatini…
Matched conditions: CRITICALLY ILL
Phase: NA • Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Apr 22, 2026 15:58 UTC