CRITICALLY ILL

This study looks at whether measuring oxygen in exhaled air through a facemask is reliable for critically ill patients who need a breathing tube. Low oxygen is a common complication during this procedure. The researchers will compare facemask readings to a more direct measurement…

This study looks back at medical records of critically ill adults in the surgical ICU to compare two common drugs (propofol and ketamine) used when placing a breathing tube. The main goal is to see if one drug is linked to fewer deaths within the first week. Researchers will also…

This study tests whether measuring a specific chest muscle (parasternal intercostal) can help doctors decide the safest time to remove a breathing tube from critically ill patients. 200 adults on ventilators for at least 24 hours will be randomly assigned to standard weaning or w…

This study looks at how the body's automatic nervous system changes when ICU patients receive continuous kidney therapy to remove extra fluid. Researchers will use a special index (ANI) to measure nerve activity and see if it relates to changes in blood pressure. The goal is to b…

This study looks at how medicines behave in the bodies of up to 2,000 critically ill children under 21 in the heart intensive care unit. Researchers collect leftover blood samples and medical data to better understand drug dosing and safety. No new drugs are given—only standard c…