CONGENITAL HEART DISEASE

This study tests a special heart valve that can be made bigger as a child grows, possibly avoiding repeat surgeries. It involves 36 children aged 18 months to 16 years who need a new pulmonary valve. The valve is placed during surgery and can later be expanded using a catheter. R…

This study looks at whether high-calorie foods and special formula can help underweight children aged 1 to 5 with congenital heart disease gain weight. About 75 children will be split into three groups: standard diet, high-calorie diet, or high-calorie diet plus formula. The goal…

This study tests whether a smartphone app powered by artificial intelligence can help adults recover better after heart surgery. 500 patients will either use the app plus standard care or standard care alone. The app gives personalized advice on medications, rehab, and warning si…

This study tests whether giving the drug lidocaine during heart surgery can reduce lung damage in infants. About 320 babies under 1 year old with congenital heart disease will receive either lidocaine or a placebo. The goal is to see if lidocaine helps them breathe better and rec…

This study looks at whether a standard chest X-ray can help find congenital heart disease in newborns. Researchers will study 60 babies in the NICU who show signs of heart issues. Each baby gets a chest X-ray within 24 hours and an echocardiogram within 72 hours to confirm the di…

This study tests whether playing active video games (exergames) on a Nintendo Switch can help children and teenagers with congenital heart disease become more physically active. The study will include 13 participants aged 8-18 who are stable after heart surgery. They will wear ac…

This study tests a nursing support program for families of children aged 1 to 3 who have had heart surgery. The program includes education and counseling sessions to help parents improve caregiving and support their child's development. Researchers will compare families who recei…

This study will test a handheld device called Intra.Ox that uses light to measure oxygen levels in the heart and other organs during complex heart surgery in children. The goal is to see if it can give surgeons quick, useful information about blood flow to help make better decisi…

This study looks at whether a special breathing technique (lung volume optimization maneuver) can improve heart and lung function in 80 children having heart surgery. The approach involves adjusting ventilator settings to find the best lung volume. Researchers will measure blood …

This study looks at how heart procedures affect the mental health of people with congenital heart disease. Researchers will check for depression, anxiety, and other psychiatric symptoms before surgery, one month after, and three months after. The goal is to help doctors better su…

This study tests a WeChat-based mini-program designed to help families care for children (up to age 12) recovering from congenital heart disease surgery. The program provides health education, peer support, and health tracking, while a comparison group receives standard phone fol…

This study will check 106 infants under 2 years old who have cholestasis (a liver condition) to see how many also have congenital heart defects. Researchers will use echocardiograms and developmental tests to understand the link. No treatment is given—the goal is to learn more ab…

This study looks at 22 children with congenital heart disease who are receiving a blood thinner called heparin through a central line. Researchers want to find out which method of drawing blood from that line gives the most accurate measurement of heparin levels. The goal is to i…

This study aims to test new MRI methods that can see tiny changes in heart muscle structure, which may help detect heart disease earlier than current tests. Researchers at the Cleveland Clinic will compare these advanced scans with standard blood tests and imaging in 1000 adults …