CONGENITAL HEART DISEASE

This study is testing a replacement heart valve for people born with certain heart defects. The valve is designed to be placed using a thin tube (catheter) instead of open-heart surgery. Researchers are checking if it is safe, works well long-term, and improves patients' quality …

This study is testing a new, adjustable heart valve for children with congenital heart disease who need surgery to replace their pulmonary valve. The valve is special because it can be expanded before surgery to fit the child's size and can be expanded again later using a cathete…

This study is testing a new medical device designed to help people born with poorly functioning pulmonary heart valves. The device combines a support structure with a replacement valve, delivered through a catheter without open-heart surgery. Researchers want to see if this appro…

This study is testing if adding nitric oxide gas to the heart-lung machine during surgery helps protect babies' brains and kidneys. It involves infants under 1 year old who need surgery to fix a congenital heart defect. Researchers will measure specific proteins in the blood befo…

This study is testing a new driving system for a heart pump designed to help children with severe heart failure. The pump supports the child's heart while they wait for a transplant. Researchers will monitor how well the new system works and how safe it is for up to 40 children w…

This study is monitoring how well a recently approved replacement heart valve works in everyday medical practice. It follows 150 patients born with specific heart defects who have received this valve. The main goal is to check if the valve is still working properly and hasn't nee…

This study is collecting real-world safety information about rivaroxaban, a blood-thinning medication, in children who have undergone Fontan heart surgery. Researchers are monitoring 61 pediatric patients to better understand the risks of major and minor bleeding events during tr…

This study is testing a new method for guiding heart catheterization procedures using real-time MRI imaging instead of X-rays. Researchers want to see if special, low-energy MRI settings can safely allow the use of standard guidewires to steer the catheter, which could reduce the…

This study is testing whether a special adhesive heart monitor patch called Zio® can be worn by children for up to 14 days. Researchers want to see if the patch sticks well to children's skin and provides clear heart rhythm readings. The study involves 36 children, ages 1 to 17, …

This study is testing a web-based decision aid designed to help parents who must make urgent, life-altering choices for a fetus or newborn diagnosed with a severe, life-threatening heart defect. Researchers are comparing parents who use the tool to those who don't, to see if it r…

This study aims to see if blood tests taken during and after pregnancy can predict future heart problems in women who were born with a heart condition. Researchers will follow 100 pregnant women with congenital heart disease to see if changes in these blood markers over time give…