COLORECTAL CANCER SCREENING

This study compares a new technique called total underwater colonoscopy (using water instead of gas to open the colon) with the standard method in over 1,000 people who had a positive stool test. The goal is to see if the water method finds more flat, hard-to-see polyps that can …

This study is developing a blood test that looks for tiny molecules called miRNAs to detect several types of digestive system cancers (like liver, pancreatic, and colon cancer) early. The goal is to create a simple, noninvasive screening tool that can be used for large population…

This study tests whether giving personalized diet and lifestyle advice to people at high risk for colorectal cancer helps them adopt healthier habits. About 800 participants will be followed for a year to see if they improve their diet, exercise, and other behaviors linked to can…

This study tests a decision aid called Protect Your Colon™ to see if it helps people aged 45-75 who are due for colorectal cancer screening choose and complete a screening test. About 184 participants will either use the tool or get usual care. The goal is to increase screening u…

This study compares two FDA-approved bowel preparation methods for colonoscopy: low-volume tablets (Suflave/Sutab) versus the standard Golytely drink. About 300 adults scheduled for colonoscopy will be randomly assigned to one of the two preps. Researchers will measure patient sa…

This study looks at whether training general practitioners in a patient-centered approach helps patients make more informed decisions about colorectal cancer screening. About 400 patients aged 50 to 74 will take part. The goal is to see if the training leads to better shared deci…

This study tests a culturally tailored education program to help more people get screened for colorectal cancer. About 50 adults aged 45-75 who are not up-to-date on screening will participate. The goal is to see if the program is practical, well-liked, and effective at increasin…

This study looks at bacteria in stool samples from 30,000 people aged 40-74 in Portugal to find new markers for early colorectal cancer detection. Researchers will compare gut microbiome patterns with standard screening tests and colonoscopy results. The goal is to develop a more…

This study talks to adults aged 45 to 54 who have never been screened for colorectal cancer, as well as health center staff, to learn what makes it easier or harder to get screened. Researchers will conduct interviews and surveys to identify barriers and find better ways to encou…

This study tests whether using a patient's existing CT scan to guide the colonoscope can make the procedure faster, less painful, and easier for doctors. About 200 adults getting a colonoscopy will be randomly assigned to either standard care or CT-assisted insertion. The goal is…

This study looks at why some people don't get a follow-up colonoscopy after a positive FIT (stool) test for colorectal cancer. Researchers will test simple strategies to help more people complete the colonoscopy, especially in underserved communities. About 45 adults aged 45-75 f…