COCAINE USE DISORDER

This study tests whether a smartphone app can help people who are already on methadone treatment reduce their use of opioids and cocaine. About 240 adults who use both drugs will either get standard methadone care or also use an app that rewards them with money for drug-free test…

This study aimed to see if exenatide, a drug used for type 2 diabetes, could reduce the desire to use cocaine. It was designed for adults who had used cocaine for at least 10 years. However, the study was withdrawn before any participants were enrolled, so no results are availabl…

This study looks at whether using a smartphone app that gives rewards for negative drug tests works for older adults with opioid, cocaine, or methamphetamine use disorders. Researchers will compare how well younger and older participants engage with the app and stay abstinent. Th…

This study looks at whether a single 25 mg dose of psilocybin (the active ingredient in magic mushrooms) can be safely given to people with cocaine use disorder who want to quit. Ten adults from Los Angeles will take the drug in a comfortable room with two clinicians present, and…

This study tests a digital program called LDART for adults who want to reduce or stop using stimulants like cocaine or methamphetamine. About 80 people in Connecticut will use the app for 28 nights. Researchers will see if the tool is easy to use and if it helps lower stimulant u…

This early-stage study looks at how the medication methylphenidate (Ritalin) might help reduce drug-related memories and cravings in people with cocaine use disorder. Fifty-one participants will receive either the drug or a placebo, then undergo brain scans and skin response test…