CHRONIC RHINOSINUSITIS WITH NASAL POLYPS
Clinical trials for CHRONIC RHINOSINUSITIS WITH NASAL POLYPS explained in plain language.
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New hope for stubborn nasal polyps: dupilumab shows promise
Disease control CompletedThis study tested the drug dupilumab in 25 adults with chronic sinusitis and nasal polyps that standard treatments couldn't control. Participants received injections for up to 52 weeks. The main goal was to see if polyp size shrank by at least 1 point on a 0-8 scale after 24 week…
Matched conditions: CHRONIC RHINOSINUSITIS WITH NASAL POLYPS
Phase: PHASE4 • Sponsor: Sanofi • Aim: Disease control
Last updated May 26, 2026 09:04 UTC
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New drug shows promise for chronic nasal polyps in chinese patients
Disease control CompletedThis study tested a drug called dupilumab in 63 Chinese adults with chronic sinusitis and nasal polyps (growths in the nose). Participants received either dupilumab injections or a placebo, along with a standard nasal steroid spray, for 24 weeks. The main goal was to see if dupil…
Matched conditions: CHRONIC RHINOSINUSITIS WITH NASAL POLYPS
Phase: PHASE3 • Sponsor: Sanofi • Aim: Disease control
Last updated May 26, 2026 08:56 UTC
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Head-to-Head drug battle: which works better for stuffy noses and asthma?
Disease control CompletedThis study compared two medications, dupilumab and omalizumab, in 360 adults with severe nasal polyps and asthma. The goal was to see which drug better shrinks polyps and improves sense of smell. Both are injected treatments that help control symptoms but do not cure the conditio…
Matched conditions: CHRONIC RHINOSINUSITIS WITH NASAL POLYPS
Phase: PHASE4 • Sponsor: Sanofi • Aim: Disease control
Last updated May 26, 2026 08:56 UTC
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Antibiotic after sinus surgery cuts polyp return rate by more than half
Disease control CompletedThis study tested whether taking a low-dose antibiotic (clarithromycin) for three months after sinus surgery could stop nasal polyps from growing back early. 100 adults aged 15-75 who had surgery for nasal polyps took part. Those who received the antibiotic had fewer symptoms and…
Matched conditions: CHRONIC RHINOSINUSITIS WITH NASAL POLYPS
Phase: NA • Sponsor: Fatima Jinnah Medical University • Aim: Disease control
Last updated May 26, 2026 08:53 UTC
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Xolair shows Real-World promise for stubborn nasal polyps
Disease control CompletedThis study checked how safe and effective Xolair is for adults with chronic sinusitis and nasal polyps that don't get better with standard treatments. It included 135 people in routine medical care. The main goal was to track side effects, and the study also measured how symptoms…
Matched conditions: CHRONIC RHINOSINUSITIS WITH NASAL POLYPS
Sponsor: Novartis Pharmaceuticals • Aim: Disease control
Last updated May 26, 2026 08:34 UTC
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New injection aims to ease sinusitis and nasal polyps Long-Term
Disease control CompletedThis study tested a new injection called TQC2731 in 59 adults with chronic sinusitis and nasal polyps. The goal was to see if it is safe and effective for long-term use. Researchers tracked side effects and changes in nasal polyp size. The treatment is meant to control the diseas…
Matched conditions: CHRONIC RHINOSINUSITIS WITH NASAL POLYPS
Phase: PHASE2 • Sponsor: Chia Tai Tianqing Pharmaceutical Group Nanjing Shunxin Pharmaceutical Co., Ltd. • Aim: Disease control
Last updated May 22, 2026 14:05 UTC
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New hope for Aspirin-Sensitive asthma sufferers: mepolizumab shows promise
Disease control CompletedThis study tested a monthly injection of mepolizumab (100 mg) versus placebo in 95 adults with severe asthma, nasal polyps, and aspirin sensitivity. The goal was to see if the drug could improve sinus symptoms, shrink nasal polyps, and reduce the need for other medications. Resul…
Matched conditions: CHRONIC RHINOSINUSITIS WITH NASAL POLYPS
Phase: PHASE4 • Sponsor: Helsinki University Central Hospital • Aim: Disease control
Last updated May 22, 2026 13:52 UTC
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New injection shows promise for stubborn nasal polyps
Disease control CompletedThis study tested whether a medication called tezepelumab, given as an injection, could reduce nasal polyps and improve symptoms in people with severe chronic sinusitis. Over 400 participants with severe symptoms who needed surgery received either the drug or a placebo for 52 wee…
Matched conditions: CHRONIC RHINOSINUSITIS WITH NASAL POLYPS
Phase: PHASE3 • Sponsor: AstraZeneca • Aim: Disease control
Last updated Apr 21, 2026 12:43 UTC
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New injection could shrink nasal polyps and ease breathing
Symptom relief CompletedThis study tested a new drug called lunsekimig in 79 adults with chronic sinusitis and nasal polyps that didn't improve with standard nasal sprays. Participants received either the drug or a placebo as a shot under the skin for 24 weeks. The goal was to see if the drug could shri…
Matched conditions: CHRONIC RHINOSINUSITIS WITH NASAL POLYPS
Phase: PHASE2 • Sponsor: Sanofi • Aim: Symptom relief
Last updated May 26, 2026 09:01 UTC
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Scientists uncover how a drug fights smell loss in sinus sufferers
Knowledge-focused CompletedThis study looked at how dupilumab improves smell in people with chronic sinusitis and nasal polyps. Researchers measured changes in inflammation inside the nose using CT scans, endoscopy, and mucus samples. The goal was to confirm that the drug works by directly reducing swellin…
Matched conditions: CHRONIC RHINOSINUSITIS WITH NASAL POLYPS
Phase: PHASE4 • Sponsor: Medical University of South Carolina • Aim: Knowledge-focused
Last updated May 26, 2026 09:00 UTC