Chronic rhinosinusitis with nasal polyps
Clinical trials for Chronic rhinosinusitis with nasal polyps explained in plain language.
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Can a biologic drug ease the burden of severe nasal polyps?
Disease control Not yet recruitingThis study follows about 100 adults in Japan who have severe chronic sinusitis with nasal polyps and are starting treatment with tezepelumab, a biologic given as a shot. Researchers will track how symptoms and quality of life change over time using a standard questionnaire called…
Matched conditions: CHRONIC RHINOSINUSITIS WITH NASAL POLYPS
Sponsor: AstraZeneca • Aim: Disease control
Last updated Aug 29, 2026 00:00 UTC
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Triple-Action nasal spray could ease chronic sinusitis
Disease control Not yet recruitingThis early-stage trial tests a nasal spray for adults with chronic sinusitis (without polyps). The spray contains stem cell exosomes to heal the nose lining, an antibiotic to kill bacteria, and an enzyme to break up thick mucus. 108 participants will use the spray twice daily for…
Matched conditions: CHRONIC RHINOSINUSITIS WITH NASAL POLYPS
Early phase 1 • Sponsor: The First Affiliated Hospital of Xinxiang Medical College • Aim: Disease control
Last updated Jun 27, 2026 13:04 UTC
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New hope for stuffy noses: experimental drug targets nasal polyps
Disease control Not yet recruitingThis study tests an investigational drug called CM326 in 212 adults with chronic sinusitis and nasal polyps. Participants will receive either CM326 or a placebo for 24 weeks, followed by an open-label period. The goal is to see if the drug shrinks polyps and eases congestion.
Matched conditions: CHRONIC RHINOSINUSITIS WITH NASAL POLYPS
Phase 3 • Sponsor: CSPC Baike (Shandong) Biopharmaceutical Co., Ltd. • Aim: Disease control
Last updated Jun 27, 2026 09:06 UTC