CHRONIC MYELOMONOCYTIC LEUKEMIA
Clinical trials for CHRONIC MYELOMONOCYTIC LEUKEMIA explained in plain language.
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New combo therapy shows promise for leukemia relapse after transplant
Disease control CompletedThis study tested a drug called guadecitabine combined with donor white blood cell infusions in 55 adults whose leukemia or MDS came back after a stem cell transplant. The goal was to see if the drug could help the donor cells fight the cancer more effectively. The treatment aims…
Matched conditions: CHRONIC MYELOMONOCYTIC LEUKEMIA
Phase: PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated May 26, 2026 06:11 UTC
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Experimental combo targets Hard-to-Treat blood cancers
Disease control CompletedThis early-phase trial tested a mix of a cancer vaccine, chemotherapy, and immunotherapy in 8 people with myelodysplastic syndrome (MDS) or acute myeloid leukemia (AML) with low blast counts. The goal was to see if the combination is safe and helps the immune system fight cancer …
Matched conditions: CHRONIC MYELOMONOCYTIC LEUKEMIA
Phase: PHASE1 • Sponsor: Roswell Park Cancer Institute • Aim: Disease control
Last updated May 26, 2026 06:10 UTC
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New Two-Step transplant shows promise for blood cancer patients
Disease control CompletedThis study tested a two-step stem cell transplant for people with blood cancers like leukemia and lymphoma. The approach uses low-dose chemo and radiation before a donor stem cell infusion, followed by drugs to prevent graft-versus-host disease. The goal was to control the cancer…
Matched conditions: CHRONIC MYELOMONOCYTIC LEUKEMIA
Phase: PHASE2 • Sponsor: Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University • Aim: Disease control
Last updated May 26, 2026 06:10 UTC
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New pill takes aim at hard-to-treat blood cancers
Disease control CompletedThis early-stage study tested a new drug called JNJ-74856665 in 153 people with acute myeloid leukemia (AML) or myelodysplastic syndromes (MDS). The main goal was to find safe doses and check for side effects. The drug works by blocking a key enzyme cancer cells need to grow. Thi…
Matched conditions: CHRONIC MYELOMONOCYTIC LEUKEMIA
Phase: PHASE1 • Sponsor: Janssen Research & Development, LLC • Aim: Disease control
Last updated May 26, 2026 06:07 UTC
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Promising combo tackles tough leukemias in early trial
Disease control CompletedThis early-phase study tested a combination of two drugs—veliparib and temozolomide—in 66 adults with acute leukemias that had come back or not responded to standard treatment. The goal was to find the safest dose and see how well the combo worked. Veliparib blocks a repair enzym…
Matched conditions: CHRONIC MYELOMONOCYTIC LEUKEMIA
Phase: PHASE1 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated May 26, 2026 05:59 UTC
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New pill shows promise against tough blood cancers in early trial
Disease control CompletedThis early-phase study tested an oral drug called NTX-301 in 22 adults with blood cancers (MDS, AML, or CMML) that had not responded to prior treatment. The main goal was to check safety and find the right dose. Researchers also looked for signs that the drug could control the di…
Matched conditions: CHRONIC MYELOMONOCYTIC LEUKEMIA
Phase: PHASE1 • Sponsor: University of Alabama at Birmingham • Aim: Disease control
Last updated May 26, 2026 05:49 UTC
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New targeted drug shows promise as Post-Transplant shield for rare blood cancers
Disease control CompletedThis study tested the drug enasidenib as a maintenance therapy after stem cell transplant in 23 people with IDH2-mutant acute myeloid leukemia or chronic myelomonocytic leukemia. The goal was to find the safest dose and see if it could help prevent the cancer from coming back. Pa…
Matched conditions: CHRONIC MYELOMONOCYTIC LEUKEMIA
Phase: PHASE1 • Sponsor: Massachusetts General Hospital • Aim: Disease control
Last updated May 22, 2026 14:04 UTC
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New Two-Step transplant shows promise for tough blood cancers
Disease control CompletedThis study tested a two-step stem cell transplant for people with high-risk blood cancers like leukemia and lymphoma. First, patients got low-dose chemotherapy and radiation to prepare the body. Then, they received donor immune cells followed by donor stem cells to help destroy c…
Matched conditions: CHRONIC MYELOMONOCYTIC LEUKEMIA
Phase: PHASE2 • Sponsor: Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University • Aim: Disease control
Last updated May 22, 2026 13:54 UTC
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Experimental cell therapy targets Hard-to-Treat leukemia
Disease control CompletedThis early-phase study tested a new cell therapy called LILRB4 STAR-T cells in one person with monocytic leukemia (a type of blood cancer). The goal was to see if the treatment is safe and can reduce cancer in the bone marrow. Researchers monitored side effects like immune reacti…
Matched conditions: CHRONIC MYELOMONOCYTIC LEUKEMIA
Phase: NA • Sponsor: Institute of Hematology & Blood Diseases Hospital, China • Aim: Disease control
Last updated May 13, 2026 15:59 UTC