CHRONIC GRAFT VERSUS HOST DISEASE
Clinical trials for CHRONIC GRAFT VERSUS HOST DISEASE explained in plain language.
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New hope for young transplant patients: Steroid-Free GVHD treatment explored
Disease control TerminatedThis study tested whether the drug ruxolitinib could be used as the first treatment for chronic graft-versus-host disease (cGVHD) in children and young adults, instead of the usual high-dose steroids. cGVHD is a serious complication after a stem cell transplant where the donor ce…
Matched conditions: CHRONIC GRAFT VERSUS HOST DISEASE
Phase: PHASE1 • Sponsor: Children's Hospital Medical Center, Cincinnati • Aim: Disease control
Last updated May 20, 2026 11:55 UTC
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New drug combo for GVHD shows promise but trial ends early
Disease control TerminatedThis study looked at whether adding the drug itacitinib to standard steroid treatment could help people with moderate to severe chronic graft-versus-host disease (cGVHD), a complication after a stem cell transplant. The goal was to control the disease, not cure it. The trial was …
Matched conditions: CHRONIC GRAFT VERSUS HOST DISEASE
Phase: PHASE2, PHASE3 • Sponsor: Incyte Corporation • Aim: Disease control
Last updated May 11, 2026 20:40 UTC