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Drug rollover trial offers ongoing hope for rare blood and transplant patients

NCT ID NCT04640025

First seen Jan 08, 2026 · Last updated May 22, 2026 · Updated 26 times

Summary

This study gives continued access to the drug itacitinib for people who were already taking it in a previous study and were doing well. It includes patients with myelofibrosis, chronic graft-versus-host disease, or bronchiolitis obliterans after a lung transplant. The goal is to keep providing the treatment as long as it helps and is safe.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Anschutz Cancer Pavilion-University of Colorado

    Aurora, Colorado, 80045, United States

  • Aou San Giovanni Di Dio E Ruggi

    Salerno, 84131, Italy

  • Azienda Ospedaliera Bianchi-Melacrino-Morelli Ospedali Riuniti

    Reggio Calabria, 89100, Italy

  • Azienda Policlinico Vittorio Emanuele

    Catania, 95123, Italy

  • City of Hope National Medical Center

    Duarte, California, 31010, United States

  • Cleveland Clinic

    Cleveland, Ohio, 44195, United States

  • Hadassah Hebrew University Medical Center Ein Karem Hadassah

    Jerusalem, 91120, Israel

  • Hospital Universitario Ramon Y Cajal

    Madrid, 28034, Spain

  • Hospital Universitario Virgen de Las Nieves

    Granada, 18012, Spain

  • Hospital of the University of Pennsylvania

    Philadelphia, Pennsylvania, 19104, United States

  • Ordensklinikum Linz Gmbh Elisabethinen

    Linz, 04020, Austria

  • Parkview Cancer Institute

    Fort Wayne, Indiana, 46845, United States

  • Providence Health

    Vancouver, British Columbia, V6Z 2A5, Canada

  • Sarah Cannon Research Institute

    Nashville, Tennessee, 37203, United States

  • Temple University Department of Thoracic Medicine and Surgery

    Philadelphia, Pennsylvania, 19140, United States

  • Texas Oncology San Antonio

    San Antonio, Texas, 78240, United States

  • Universitaire Ziekenhuis Leuven - Gasthuisberg

    Leuven, 03000, Belgium

  • Universitatsklinikum Halle (Saale)

    Halle, D06120, Germany

  • University Hospital Mannheim

    Mannheim, 68167, Germany

  • University Hospital of West Attica - Attikon

    Chaïdári, 12462, Greece

  • University Medical Centre Hamburg-Eppendorf Centre of Oncology

    Hamburg, 20251, Germany

Conditions

Explore the condition pages connected to this study.