Rollover study offers ongoing access to experimental drug for rare blood and transplant conditions
NCT ID NCT04640025
First seen Jan 08, 2026 · Last updated May 16, 2026 · Updated 24 times
Summary
This study gives continued access to itacitinib for 18 patients who were already benefiting from the drug in earlier trials. It covers three serious conditions: myelofibrosis (a bone marrow disorder), bronchiolitis obliterans after lung transplant, and chronic graft-versus-host disease after stem cell transplant. Patients stay on the same dose they received before, as long as it helps them and side effects are manageable.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Anschutz Cancer Pavilion-University of Colorado
Aurora, Colorado, 80045, United States
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Aou San Giovanni Di Dio E Ruggi
Salerno, 84131, Italy
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Azienda Ospedaliera Bianchi-Melacrino-Morelli Ospedali Riuniti
Reggio Calabria, 89100, Italy
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Azienda Policlinico Vittorio Emanuele
Catania, 95123, Italy
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City of Hope National Medical Center
Duarte, California, 31010, United States
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Cleveland Clinic
Cleveland, Ohio, 44195, United States
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Hadassah Hebrew University Medical Center Ein Karem Hadassah
Jerusalem, 91120, Israel
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Hospital Universitario Ramon Y Cajal
Madrid, 28034, Spain
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Hospital Universitario Virgen de Las Nieves
Granada, 18012, Spain
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Hospital of the University of Pennsylvania
Philadelphia, Pennsylvania, 19104, United States
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Ordensklinikum Linz Gmbh Elisabethinen
Linz, 04020, Austria
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Parkview Cancer Institute
Fort Wayne, Indiana, 46845, United States
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Providence Health
Vancouver, British Columbia, V6Z 2A5, Canada
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Sarah Cannon Research Institute
Nashville, Tennessee, 37203, United States
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Temple University Department of Thoracic Medicine and Surgery
Philadelphia, Pennsylvania, 19140, United States
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Texas Oncology San Antonio
San Antonio, Texas, 78240, United States
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Universitaire Ziekenhuis Leuven - Gasthuisberg
Leuven, 03000, Belgium
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Universitatsklinikum Halle (Saale)
Halle, D06120, Germany
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University Hospital Mannheim
Mannheim, 68167, Germany
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University Hospital of West Attica - Attikon
Chaïdári, 12462, Greece
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University Medical Centre Hamburg-Eppendorf Centre of Oncology
Hamburg, 20251, Germany
Conditions
Explore the condition pages connected to this study.