CHRONIC GRAFT VERSUS HOST DISEASE
Clinical trials for CHRONIC GRAFT VERSUS HOST DISEASE explained in plain language.
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New combo therapy shows promise for tough transplant complication
Disease control CompletedThis study tested whether adding a low dose of the drug Interleukin-2 (IL-2) to a standard therapy called Extracorporeal Photopheresis (ECP) could help people with chronic graft-versus-host disease (cGVHD) that did not improve with steroids. cGVHD is a serious condition where don…
Matched conditions: CHRONIC GRAFT VERSUS HOST DISEASE
Phase: PHASE2 • Sponsor: Dana-Farber Cancer Institute • Aim: Disease control
Last updated May 26, 2026 04:24 UTC
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New hope for kids with chronic graft-versus-host disease?
Disease control CompletedThis study tested the drug ibrutinib in children with chronic graft-versus-host disease (cGVHD), a complication after a stem cell transplant. The goal was to find the best dose and check safety. Fifty-nine children aged 1 to 22 took part. The study is now complete.
Matched conditions: CHRONIC GRAFT VERSUS HOST DISEASE
Phase: PHASE1, PHASE2 • Sponsor: Pharmacyclics LLC. • Aim: Disease control
Last updated May 20, 2026 11:56 UTC
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New hope for GVHD patients after multiple failed treatments
Disease control CompletedThis study tested a drug called axatilimab in 41 people with chronic graft-versus-host disease (cGVHD), a complication after a stem cell transplant where donor cells attack the body. Participants had already tried at least 2 other treatments. The goal was to find a safe dose and …
Matched conditions: CHRONIC GRAFT VERSUS HOST DISEASE
Phase: PHASE1, PHASE2 • Sponsor: Syndax Pharmaceuticals • Aim: Disease control
Last updated May 18, 2026 12:12 UTC