CHRONIC GRAFT-VERSUS-HOST-DISEASE
Clinical trials for CHRONIC GRAFT-VERSUS-HOST-DISEASE explained in plain language.
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New combo therapy tested for tough transplant complication
Disease control CompletedThis study tested whether adding a drug called Interleukin-2 (IL-2) to a standard light-based blood treatment (ECP) could help control chronic graft-versus-host disease (GVHD) in adults. The 25 participants had GVHD that did not improve with steroid medications. They received ECP…
Matched conditions: CHRONIC GRAFT-VERSUS-HOST-DISEASE
Phase: PHASE2 • Sponsor: Dana-Farber Cancer Institute • Aim: Disease control
Last updated Mar 30, 2026 14:30 UTC
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New hope for kids battling transplant complications
Disease control CompletedThis study aimed to find a safe and effective dose of the drug ibrutinib for children and young adults with chronic graft-versus-host disease (cGVHD), a serious complication that can occur after a stem cell transplant. It involved 59 participants aged 1 to 22 years who had modera…
Matched conditions: CHRONIC GRAFT-VERSUS-HOST-DISEASE
Phase: PHASE1, PHASE2 • Sponsor: Pharmacyclics LLC. • Aim: Disease control
Last updated Mar 30, 2026 14:30 UTC
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New drug tested for tough transplant complication
Disease control CompletedThis study tested an experimental drug called axatilimab for people with chronic graft-versus-host disease (cGVHD) that hadn't improved after at least two previous treatments. The trial aimed to find a safe dose and see if the drug could help control the disease. It involved 41 p…
Matched conditions: CHRONIC GRAFT-VERSUS-HOST-DISEASE
Phase: PHASE1, PHASE2 • Sponsor: Syndax Pharmaceuticals • Aim: Disease control
Last updated Mar 23, 2026 15:17 UTC