CELIAC DISEASE

This study tested an experimental drug called KAN-101 in 55 adults with celiac disease who had been on a gluten-free diet for at least a year. The goal was to see if the drug could reduce intestinal damage caused by a two-week gluten challenge. Results showed that KAN-101 helped …

This study tested an experimental drug called TAK-101 in 102 adults with celiac disease who were already eating gluten-free. The goal was to see if the drug could reduce the immune system's reaction to gluten and lessen symptoms. Participants received two doses of TAK-101 or a pl…

This study tested whether the drug ritlecitinib can protect people with celiac disease from gut damage and symptoms when they eat gluten. 62 adults with well-controlled celiac disease (on a gluten-free diet) took either the drug or a placebo along with a daily gluten challenge. T…

This study tested a new treatment called TPM502 in 28 adults with celiac disease. The goal was to see if it is safe and can help the body become less sensitive to gluten. Participants received two infusions of TPM502 or a placebo, two weeks apart, and underwent gluten challenges …

This study tested whether a probiotic called LP-LDL can lower cholesterol in 50 adults with celiac disease. Participants took the probiotic for several weeks. The goal was to see if it reduces heart disease risk factors like high cholesterol and BMI. The study is complete, and re…

This early-stage study tested a single oral dose of HB-2121 in 18 adults (some with celiac disease, some healthy) to see if it is safe and how the body processes it. Participants were monitored for 30 days with clinic visits and daily symptom questionnaires. The goal was to check…

This study tested an experimental drug called PRV-015 in 388 adults with celiac disease who still had symptoms like belly pain, bloating, and diarrhea despite following a strict gluten-free diet. The goal was to see if the drug could reduce these symptoms over 24 weeks. Participa…

This study looked at whether a specific type of oat called Saul is safe for adults with celiac disease whose condition is well-controlled. Forty participants ate 50 grams of gluten-free Saul oat flakes every day for two weeks. Researchers tracked symptoms and blood markers to see…

This study looked at whether cutting out certain carbs (FODMAPs) can reduce ongoing stomach issues in people with celiac disease who already follow a strict gluten-free diet. Researchers surveyed and then ran a controlled trial with 80 adults. The goal was to see if a low FODMAP …

This study involved 33 adults with celiac disease who ate small amounts of different gluten types to see how their immune systems reacted. The goal was to find better ways to test whether processed gluten in foods is safe for people with celiac disease. Participants completed fiv…

This study looked at whether taking a laxative (Polyethylene Glycol) before a capsule endoscopy helps doctors see the small intestine better. 230 adults were randomly assigned to take the laxative as a single dose, a split dose, or just clear liquids. The goal was to see which me…