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Can a pill stop gluten damage in celiac patients?

NCT ID NCT05636293

First seen Nov 17, 2025 · Last updated May 22, 2026 · Updated 25 times

Summary

This study tested whether the drug ritlecitinib can protect people with celiac disease from gut damage and symptoms when they eat gluten. 62 adults with well-controlled celiac disease (on a gluten-free diet) took either the drug or a placebo along with a daily gluten challenge. The goal was to see if the drug could prevent the intestinal injury and discomfort typically caused by gluten.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Massachusetts General Hospital

    Boston, Massachusetts, 02114, United States

Conditions

Explore the condition pages connected to this study.