New drug may shield celiac patients from accidental gluten exposure

NCT ID NCT05636293

First seen Nov 17, 2025 · Last updated May 15, 2026 · Updated 22 times

Summary

This study tested whether the drug ritlecitinib can prevent intestinal damage and symptoms caused by gluten in people with celiac disease who are already on a gluten-free diet. 62 adults with inactive celiac disease took either the drug or a placebo along with a small amount of gluten. The goal was to see if the drug could protect the small intestine and reduce symptoms during a gluten challenge.

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Contacts and locations

Locations

  • Massachusetts General Hospital

    Boston, Massachusetts, 02114, United States

Conditions

Explore the condition pages connected to this study.