CARDIAC DISEASE

This study compares two different blood vessels used as grafts during heart bypass surgery in women. Researchers want to see whether using a vein from the leg (with a special 'no-touch' technique) or an artery from the arm stays open better over time. The goal is to improve long-…

This large study is testing if a short course of the anti-inflammatory drug colchicine, taken around the time of heart surgery, can reduce damage to organs like the heart and lungs. It will involve 768 patients undergoing planned heart surgery with a heart-lung machine. Researche…

This study is testing the safety and performance of two specific heart pacing leads when placed in a particular area of the heart's electrical system. Researchers will follow 200 adult patients for 6 months after implant to check for complications like infection, lead movement, o…

This study is testing if giving the blood thinner heparin during a common heart test prevents a complication where the wrist artery used for access gets blocked. About 1,623 patients having a planned heart catheterization through the wrist will be randomly assigned to receive no …

This large Phase 3 trial is testing whether adding two common medications to standard care can prevent future strokes, heart attacks, and other major vascular problems in high-risk patients who have recently had a stroke. It will compare a low-dose anti-inflammatory drug (colchic…

This study is testing whether new artificial intelligence (AI) software can improve heart MRI scans. Researchers will compare AI-enhanced scans to standard scans in 50 adults who need a heart MRI. They will measure scan time, image quality, and how satisfied patients are with the…

This study is testing if a specific nerve block, given after heart surgery, can help control pain better. Researchers want to see if it reduces the need for strong opioid painkillers and lowers patients' pain scores. The study will involve 75 adults having planned heart surgery, …

This large registry study aims to monitor the long-term safety and performance of Boston Scientific heart rhythm devices in real-world patients. Researchers will follow approximately 12,500 people who receive these implanted devices, collecting data for as long as the devices rem…

This study aims to understand how medications behave in the bodies of critically ill children with heart conditions. Researchers will observe approximately 2,000 children under 21 who are already receiving standard medications in the cardiac intensive care unit. The study collect…

This study aims to collect information to help doctors better predict which older patients are at higher risk of complications after hip fracture surgery. It will compare two different assessment tools: a standard heart health check and a newer 'frailty score' designed for hip fr…