BRAIN TUMOR

This early-stage study tested a new oral medication called CUDC-907 in children and young adults whose cancers had returned or stopped responding to standard treatments. The main goals were to check for side effects and find the safest dose for children, since this drug had only …

This early-stage study tested whether combining two existing cancer drugs (pembrolizumab and vorinostat) with standard chemotherapy and radiation is safe for people newly diagnosed with glioblastoma, an aggressive brain tumor. The trial involved 21 participants to determine the h…

This study tested a new type of MRI contrast dye called RVP-001, which is based on manganese instead of the commonly used gadolinium. It involved 18 adults with known brain or spinal cord lesions from conditions like tumors or multiple sclerosis. The main goal was to see if RVP-0…

This study tested a new, highly sensitive ultrasound method to create maps of active brain areas during surgery for brain tumors or lesions. The goal was to see if this new, real-time method could work as well as the current gold-standard mapping techniques used by surgeons. It i…

This study looked at whether a special type of PET scan (FDOPA-PET) can better tell the difference between brain tumors and non-cancerous brain lesions. Researchers analyzed past scan data from 74 patients who had suspicious brain findings on an MRI. The goal was to find the best…

This small, early-stage study tested a new type of combined PET and MRI scan to see if it could take clearer pictures of brain tumors. It involved 5 adult patients with new or suspected returning brain tumors who were already scheduled for treatment. The goal was to gather initia…

This study tested whether a 12-week home exercise program could improve memory and attention problems in children who had radiation therapy for brain tumors. Thirty-six children, ages 8-17, were split into two groups. One group started the exercise program right away, while the o…

This study tested whether a sedative drug called dexmedetomidine could help protect the brain during surgery to remove a tumor. Researchers gave the drug or a placebo to 56 patients during their operation to see if it reduced brain stress and inflammation. The main goal was to se…

This study tested a special talk therapy program called CALM, designed to help people with advanced brain cancer cope with emotional distress, depression, and anxiety about death. It compared the CALM program to the usual care patients receive. The main goal was to see if the the…

This study tested whether watching 360° virtual reality movies could help reduce fear and anxiety in cancer patients about to begin radiation therapy. Researchers enrolled 292 adults with breast, lung, prostate, head and neck cancers, or brain tumors. Patients watched VR movies s…

This small pilot study tested whether a new telehealth program called C-SMART is practical and acceptable for brain tumor patients experiencing mild thinking and memory problems. The main goal was to see if patients and their caregivers could be recruited and complete the program…

This study tested whether a short online training course could improve the ability of emergency department doctors and nurses to accurately read CT scans of the head. The goal was to see if this training could help them identify critical problems like strokes or brain bleeds more…

This study aimed to better understand brain and spinal cord tumors by observing over 1,200 adult patients over time. Researchers collected medical information, scans, and tissue samples to learn how these cancers progress and to identify areas for future treatment research. The s…

This study followed children and young adults who had proton radiation for brain or spinal cord tumors. Researchers wanted to see how their thinking skills, emotions, and behavior changed over time, and whether they needed special help in school. They collected this information b…