New scan method aims to sharpen brain tumor images
NCT ID NCT04173104
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This early study tested a new imaging technique that combines a special tracer ([18F]PARPi) with PET and MRI scans to get clearer pictures of brain tumors. Five adults with new or suspected returning brain tumors took part. The goal was to see how well the tracer highlights tumor cells, which could help doctors better detect and monitor brain cancer.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Early phase 1
The earliest testing in people: a first look at safety, in a very small group.
- Participants
-
5 people
The number who actually took part.
- Started
-
Nov 2019
- Finished
-
Feb 2026
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
18 years and older
- Sex
-
Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patients with new or suspected recurrent brain tumors (including suspected recurrent brain tumors showing growth from any preceding scan) * Age \>/= 18 years * Minimum at least one brain lesion size \>/= 1.5cm diameter * Scheduled to undergo treatment at MSK * Willingness to sign informed consent * Able to receive intravenous gadolinium contrast per MSK Department of Radiology guidelines Exclusion Criteria: * Any contraindication to 3T MRI (PET/MR scanner is 4.0 Tesla) * Pregnancy or breast-feeding women
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Brain cancer are added.
Genom att skicka in godkänner du våra Användarvillkor
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Memorial Sloan Kettering Cancer Center
New York, New York, 10065, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- One extra radiation dose after standard brain cancer therapy: can it boost the immune system?
- Can doctors watch brain metastases instead of zapping them?
- Zapping the brain to restore lost vision
- Brain surgery delirium: can real-time monitoring protect older patients?
- Music as medicine: could ukulele lessons rebuild young brains after cancer?
- Can trained immune cells outsmart brain tumors?