BRADYCARDIA

This study is testing a pacemaker lead placed in a specific area of the heart called the left bundle branch area. The goal is to see if this placement is safe and helps the heart beat more naturally in people with slow heart rates. About 140 participants will get the lead and be …

This study compares two pacemaker methods for people with a slow heart rate: standard right ventricular pacing and a newer 'physiological pacing' that targets the heart's natural conduction system. Researchers will track 2,600 participants over time to see which method better pre…

This study tests a new way to program pacemakers to help lower blood pressure in people who have both high blood pressure and a slow heart rate. About 30 adults who already have or need a special pacemaker will try two different setup sessions. Researchers will check if the new s…

This study compares a new pacing method called conduction system pacing (CSP) to standard pacing for people with a slow heart rate and a wide QRS pattern on their ECG. The goal is to see if CSP better preserves the heart's pumping ability over one year. About 120 adults who need …

This study looks at a new way to pace the heart called left bundle branch area pacing (LBBAP) in 200 people with conditions like slow heart rate or heart failure. The goal is to see if it's safe and works well compared to standard pacing. Participants will be followed for 6 month…

This study follows 1,805 people who already have an Aveir DR leadless pacemaker to see how safe it is over 5 years. The pacemaker helps control slow heart rhythms without wires. Researchers will track complications shortly after implant and for years afterward using real-world da…

This study is testing a new, wire-free pacemaker called LivIQ in 325 people who need a pacemaker for a slow heartbeat. The goal is to see if it is safe and works well to keep the heart beating at the right pace. Participants will be followed for several months to check the device…

This study tests a new ultra-high frequency ECG (UHF-ECG) to see if it can better diagnose ventricular electrical dyssynchrony — a condition where the heart's lower chambers don't beat in sync. Researchers will compare it to a standard 12-lead ECG in 360 adults with bradycardia o…

This study compares two ultrasound-guided nerve blocks—supra-inguinal fascia iliaca block and pericapsular nerve group block—to see which one better reduces pain when positioning patients for spinal anesthesia during femur fracture surgery. Seventy adults with a broken femur will…

This study compares three sedation approaches—using dexmedetomidine, propofol, or both—during cataract surgery in 1,000 adults. Researchers will measure how well each method sedates patients, affects heart rate and blood pressure, and causes side effects like nausea. The goal is …

This study compares two types of ultrasound-guided nerve blocks (supra-inguinal and infra-inguinal fascia iliaca blocks) in 60 adults aged 30-60 undergoing thigh or knee surgery. The goal is to see which block makes it easier for patients to get into position for spinal anesthesi…

This study tests whether adjusting a pacemaker to a personalized, optimal heart rate can improve symptoms and quality of life in people with heart failure and a slow heartbeat. About 106 adults with heart failure who need a permanent pacemaker will be randomly assigned to either …

This study tests whether adding dexmedetomidine or dexamethasone to a standard numbing medicine (ropivacaine) helps pain relief start faster during arm surgery. About 66 adults having upper limb surgery will receive one of the two combinations. The goal is to see which approach p…

This study follows 1000 people with slow heart rates who already have a specific pacemaker. Researchers will use the pacemaker's data to track sleep apnea and daily activity over time. They want to see if this information can predict serious events like heart attack, stroke, or e…

This study looks at the electrical signals in the heart during a special type of pacing called left bundle branch area pacing (LBBAP), used in people with heart failure or slow heart rates. Researchers will measure these signals at different pacing strengths and body positions in…

This study looks at whether playing womb-like sounds to preterm infants can help their brains mature and control breathing more steadily. Researchers will monitor 34 babies born at 29-33 weeks for breathing pauses, low oxygen, and slow heart rate. The goal is to understand how ea…

This study monitors how long Medtronic heart devices (like pacemakers) last and how often they have problems. It includes up to 20,000 people who have or will get one of these devices. The goal is to collect real-world data to improve future device safety and performance.

This study is for people with heart failure or a slow heartbeat who are already scheduled to get a pacemaker. Researchers will take extra measurements during the procedure to see if pacing a specific part of the heart (the His bundle) can improve electrical conduction. The goal i…

This study watches how well a small heart monitor (BIOMONITOR III) works in routine medical care for 1400 people. It tracks how quickly the device finds hidden heart rhythm problems like atrial fibrillation or fainting spells. The goal is to learn about the device's real-life per…

This study tests a portable ECG system that helps doctors monitor the placement of a pacing lead in the heart during a pacemaker or similar device implantation. About 55 adults who need this procedure will take part. The goal is to see if the portable system works as well as stan…