New study tests which drug makes arm surgery pain blocks work faster
NCT ID NCT07290595
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study compares two drugs, dexmedetomidine and dexamethasone, when added to a standard local anesthetic (ropivacaine) for a nerve block in the shoulder area. The goal is to see which combination provides faster pain relief for patients undergoing arm surgery. 66 adults aged 18-70 are being recruited. The trial is currently enrolling participants.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Ropivacaine with either Dexmedetomidine or Dexamethasone
- What this could lead to
- If successful, this could show that one of these drug combinations provides faster and longer-lasting pain relief for arm surgeries, potentially improving patient comfort and recovery.
- What could go wrong
- This is a small, early-phase study (66 participants) comparing two established drugs, so any benefits may be modest. Results may not apply to all patients or surgeries.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Phase 2/3
Runs two stages together: whether the treatment works, then large-scale confirmation.
- Participants
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About 66 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jan 2025
- Expected to finish
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Mar 2026
An estimate. End dates often move.
- Lead sponsor
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A government agency
The lead sponsor is a government body.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 70 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria * Patients scheduled for upper limb surgery below mid-humerus level * Patients aged 18 to 70 years * Patients with ASA class I, II and III * Male and non-pregnant females Exclusion Criteria * Patients refusal * Patients with pre-existing peripheral neuropathy of the upper limb * Patients with the Infection at block site * Patients with history of ischemic heart disease * Patients with bleeding disorder or deranged coagulation profile * Patients with known history of allergy to local anaesthetic or any other drugs used
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Sahiwal Medical College, Sahiwal
RECRUITINGSāhīwāl, Punjab Province, 57000, Pakistan
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Other studies related to the condition(s) this trial covers.
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