BLEEDING

This study tested whether a medicine called tranexamic acid (TXA) can reduce blood loss in women having breast cosmetic surgery. 60 women took part, and researchers measured blood loss and related lab values. The goal is to see if TXA helps control bleeding during these procedure…

This study tested two ways of using a breathing machine during heart surgery that requires a heart-lung machine. One group received no breaths during that time, while the other received small, gentle breaths. The goal was to see which approach better prevents serious lung complic…

This study tested whether a drug called tranexamic acid (TXA) can reduce blood loss during abdominoplasty (tummy tuck) surgery. 60 adults scheduled for the procedure were included. Researchers measured blood loss and blood markers to see if TXA helps control bleeding.

This study tested whether a pathogen-reduced blood product (INTERCEPT fibrinogen complex) can control bleeding better than standard cryoprecipitate in adults undergoing heart or liver transplant surgery. The goal was to see if having this product readily available reduces the nee…

This study tested two different treatments for bleeding after heart surgery in 31 young children (up to 2 years old). One group received a purified clotting protein (fibrinogen concentrate), the other received a standard blood product (cryoprecipitate). The goal was to see if the…

This study tested whether tranexamic acid, a drug that helps blood clot, can lower the chance of wound infections after gastrointestinal surgery. Over 3,300 adults at higher risk for complications took part. The goal was to see if this simple, low-cost approach could improve reco…

This study tested a new method to prevent blood clots in dialysis machines for critically ill patients who are at high risk of bleeding. Instead of using the standard blood thinner heparin, the method uses a special calcium-free citrate solution in the dialysis fluid, with calciu…

This study tested the WATCHMAN FLX Pro device in 949 people with atrial fibrillation (an irregular heartbeat) to see how well it prevents strokes. The device is implanted to close off a part of the heart where clots can form. Researchers measured safety and effectiveness in real-…

This study tested whether a newer blood thinner (rivaroxaban) is safer and more cost-effective than the standard drug warfarin for patients who develop atrial fibrillation after heart surgery. About 100 adults who had open-heart surgery and then experienced a new irregular heartb…

This study looked at how well and how safely the Obsidio device blocks blood vessels to control bleeding from hypervascular tumors. It involved 125 patients in the U.S. who were treated with Obsidio. The main goals were to see if the device successfully blocked the target vessels…

This study looked at whether using a person's genetic information to choose their blood thinner (clopidogrel or an alternative) leads to better outcomes after a heart procedure. About 283 adults with chronic coronary artery disease who had a stent placed were split into two group…

This study involved 927 patients with blood disorders who needed a central line (a special IV). Researchers wanted to see if using a lower platelet count threshold (10,000 instead of 50,000) before the procedure would still be safe. They focused on moderate to severe bleeding eve…

This study looked at 167 adults with atrial fibrillation or flutter who were scheduled for their first catheter ablation. Researchers measured stroke and bleeding risk scores before the procedure and again at 3, 6, and 12 months after. They also used heart monitors and smartwatch…

This study tested a new method to stop bleeding after a common heart procedure (transradial catheterization). The goal was to see if combining a lower dose of blood thinner with pressing on a nearby artery could reduce bleeding, bruising, and artery blockage. 451 adults took part…

This study looked at 278 adults on a heart-lung machine (VA ECMO) to find early warning signs of dangerous bleeding. Researchers collected patient details, medical history, and lab results to identify which factors made major bleeding more likely. The goal is to help doctors prev…

This early-stage study tested a vaginal ring that releases two drugs (dapivirine and levonorgestrel) in 40 healthy HIV-negative women. The goal was to measure how the body absorbs the drugs and check for safety and bleeding changes over 90 days. Results will help design future st…

This study looked back at the records of over 9,000 people who had weight-loss (bariatric) surgery. The goal was to find what factors might increase the risk of bleeding during or within 30 days after surgery. By identifying these predictors, doctors hope to create a scoring syst…