BLEEDING

This study looks at doing two heart procedures at the same time in people with atrial fibrillation (an irregular heartbeat). The first uses targeted energy to fix the heart's electrical signals, and the second closes a small pouch in the heart to lower stroke risk. Researchers wa…

This study tests if a newer blood thinner called apixaban works better and causes fewer side effects than the standard drug warfarin in people with advanced heart failure who have a HeartMate 3 heart pump. About 460 adults who have had the pump for at least 3 months will be rando…

This study tests a new procedure using an endoscopic ultrasound to guide the injection of materials that block part of the spleen's blood supply. The goal is to lower the risk of life-threatening bleeding from enlarged veins in the stomach and esophagus in people with liver cirrh…

This study tests a new device called EmboBio that doctors use to stop bleeding in the belly or pelvic area. The device is placed inside an artery to block blood flow and control bleeding. The study will include 45 adults in France and will check if the device is safe and works we…

This study tests whether giving tranexamic acid (TXA) during weight-loss surgery can reduce blood loss in patients with a very high body mass index (BMI over 45). About 128 high-risk patients will receive TXA, and doctors will measure bleeding during and after surgery, as well as…

This study tests whether giving dry plasma to people with life-threatening bleeding before they reach the hospital can improve survival. Researchers will compare dry plasma to standard fluids in 650 adults with signs of bleeding shock. The goal is to see if this approach reduces …

This study will look back at the medical records of 50 adult ICU patients with COVID-19 who needed a special life support machine (VV-ECMO). The goal is to understand how often these patients have serious bleeding or blood clots, and how blood transfusions and blood thinners affe…

This study aims to create a simple blood test algorithm to help doctors manage bleeding more precisely during open heart surgery. Researchers will analyze leftover blood samples from 140 patients to see if a special test called thromboelastography (TEG) can guide targeted treatme…

This study looks at how safe current blood thinner management is for 700 cancer patients who need surgery or medical procedures. Researchers will track bleeding and clotting problems within 30 days after surgery. The goal is to learn how to improve care and lower these risks in t…

This study looks at whether frailty can help predict bleeding in older adults (65+) who have had a heart attack or unstable angina. Researchers will follow 850 patients for up to 6 months to see if adding frailty to standard risk tools improves bleeding predictions. The goal is t…