New dialysis method could reduce bleeding risks in critically ill patients

NCT ID NCT03842657

Completed Disease control Sponsor: University Hospital, Toulouse Source: ClinicalTrials.gov ↗

First seen Jan 04, 2026 · Last updated May 21, 2026 · Updated 22 times

Summary

This study tested a new method to prevent blood clots in dialysis machines for critically ill patients who are at high risk of bleeding. Instead of using the standard blood thinner heparin, the method uses a special calcium-free citrate solution in the dialysis fluid, with calcium given back to the patient separately. The goal was to see if this approach works better than using a special dialysis filter that is coated with heparin. The study involved 97 patients who needed two long dialysis sessions.

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Contacts and locations

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Locations

CHU Toulouse

Toulouse, France
Montpellier Hospital

Montpellier, France
Nimes Hospital

Nîmes, France
Pellegrin Hospital

Bordeaux, France
Tenon Hospital

Paris, France

Conditions

Explore the condition pages connected to this study.

BLEEDING HEMODIALYSIS COMPLICATION