BASAL CELL CARCINOMA

This study tests whether a combination of two immunotherapy drugs (Opdualag) works better than one drug (nivolumab) alone for people with high-risk basal cell skin cancer. About 30 participants will receive the treatment before surgery to see if it shrinks or eliminates the tumor…

This study tests whether giving immunotherapy (cemiplimab alone or with fianlimab) before surgery can shrink advanced basal cell skin cancers of the head and neck. About 70 adults will receive 2 to 6 infusions before their operation. The goal is to see if the tumors respond enoug…

This study looks at whether giving radiation therapy after a targeted drug (sonic hedgehog inhibitor) has fully cleared advanced basal cell skin cancer can stop the cancer from returning. About 65% of patients see the cancer come back after stopping the drug alone. The study will…

This study tests whether the drug nivolumab, alone or combined with relatlimab or ipilimumab, can shrink or control advanced basal cell skin cancer that cannot be removed by surgery or has spread. About 57 adults with this condition will receive treatment. The goal is to see how …

This early-stage study tests a new treatment called MQ710, made from a modified virus, for people with advanced solid tumors that have not responded to standard therapies. The treatment is injected directly into tumors, either alone or with the immunotherapy drug pembrolizumab. T…

This study tests a new, non-invasive imaging device called LC-OCT that takes detailed pictures of skin cancer before surgery. The goal is to see if it can help doctors better identify where the cancer ends, so they can remove it all in one go. About 60 adults with a common type o…

This study tests whether giving cancer treatment at home is preferred over going to a clinic. It involves 27 adults with various cancers in the Florida Panhandle. The goal is to see if home care improves patient satisfaction and is safe.

This study is testing a new tool that predicts whether immunotherapy will work for people with melanoma and other skin cancers. Researchers will collect tumor tissue, blood, and stool samples from 1,000 participants and compare the tool's predictions to actual treatment outcomes.…

This study tests whether artificial intelligence can help surgeons analyze microscope images of skin cancer tissue during surgery. The goal is to give surgeons instant feedback on whether they are looking at cancer, inflammation, or healthy tissue. The study will enroll 1000 pati…

This study tests if a special laser probe (Raman spectroscopy) can measure how far skin cancer spreads. About 20 adults with basal or squamous cell skin cancer will have their tumors scanned with the probe. The goal is to see if the laser can tell the difference between cancer an…

This study looks at how photodynamic therapy (PDT) changes the immune system's reaction to basal cell carcinoma (BCC), a common skin cancer. Researchers will analyze tumor and blood samples from 28 adults scheduled for surgery to understand immune cell activity. The goal is to fi…