ARTHROPATHY OF KNEE
Clinical trials for ARTHROPATHY OF KNEE explained in plain language.
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Knee surgery infection prevention: one dose may be enough
Disease control CompletedThis study looked at the best way to give antibiotics before and after knee replacement surgery to prevent joint infections. About 1,770 adults having elective knee replacement took part. Researchers compared a single dose before surgery versus a longer 24-hour course to see whic…
Matched conditions: ARTHROPATHY OF KNEE
Phase: PHASE4 • Sponsor: Duke University • Aim: Disease control
Last updated May 14, 2026 12:06 UTC
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Simple pill before joint surgery may prevent painful urinary blockage
Prevention CompletedThis study tested whether taking tamsulosin, a drug used for prostate problems, can prevent urinary retention after hip or knee replacement surgery. 170 men took the drug or a placebo for five days before and two days after surgery. The goal was to see if the drug reduced the nee…
Matched conditions: ARTHROPATHY OF KNEE
Phase: PHASE4 • Sponsor: Kantonsspital Graubünden • Aim: Prevention
Last updated May 18, 2026 12:07 UTC
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Which nerve block gets knee replacement patients moving faster?
Symptom relief CompletedThis study looked at two different nerve block methods to control pain and help people walk sooner after total knee replacement surgery. 90 adults having knee replacement under spinal anesthesia received either a fascia iliaca block or a combination of adductor canal and IPACK bl…
Matched conditions: ARTHROPATHY OF KNEE
Sponsor: Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital • Aim: Symptom relief
Last updated May 26, 2026 11:46 UTC
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Drain debate: new study questions need for drains in knee replacement
Symptom relief CompletedThis study looked at whether using a surgical drain after knee replacement surgery helps reduce pain. Sixty patients over age 60 having knee replacement were included. The researchers compared pain levels before surgery and at discharge between those who got a drain and those who…
Matched conditions: ARTHROPATHY OF KNEE
Phase: NA • Sponsor: Hospital Universitario Reina Sofia de Cordoba • Aim: Symptom relief
Last updated May 26, 2026 11:45 UTC
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Robot vs. surgeon: knee replacement showdown!
Symptom relief CompletedThis study compared robotic-assisted knee replacement to the standard manual surgery in 95 patients with knee arthritis. The goal was to see if the robotic method leads to better knee function, less pain, and higher satisfaction over two years. Both techniques aim to improve qual…
Matched conditions: ARTHROPATHY OF KNEE
Phase: NA • Sponsor: Hospital de Terrassa • Aim: Symptom relief
Last updated May 26, 2026 11:31 UTC
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Weight loss before knee surgery shows promise in small trial
Symptom relief CompletedThis study tested whether a weight loss program before total knee replacement helps people with obesity have better outcomes. 24 adults aged 50-75 with a BMI between 35 and 40 were randomly assigned to either a 3-month very low-calorie diet and exercise program before surgery, fo…
Matched conditions: ARTHROPATHY OF KNEE
Phase: NA • Sponsor: University of Kansas Medical Center • Aim: Symptom relief
Last updated May 26, 2026 11:29 UTC
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Knee surgery showdown: to keep or cut the fat pad?
Symptom relief CompletedThis study looked at 377 people with knee osteoarthritis who needed a total knee replacement. It compared what happens when surgeons keep the infrapatellar fat pad (a small pad of fat in the knee) versus removing it. The goal was to see which approach leads to better pain relief,…
Matched conditions: ARTHROPATHY OF KNEE
Phase: NA • Sponsor: Zhujiang Hospital • Aim: Symptom relief
Last updated May 18, 2026 12:03 UTC
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Blood enzyme may predict knee stiffness after replacement
Knowledge-focused CompletedThis study looked at whether a blood enzyme called tryptase can help predict knee stiffness and pain after total knee replacement. Researchers measured tryptase levels before and after surgery in 219 people with knee arthritis. The goal was to see if changes in this enzyme are li…
Matched conditions: ARTHROPATHY OF KNEE
Sponsor: Mayo Clinic • Aim: Knowledge-focused
Last updated May 26, 2026 11:37 UTC