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Simple pill before joint surgery may spare men from catheter

NCT ID NCT03808155

Prevention Sponsor: Kantonsspital Graubünden Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tested whether taking tamsulosin, a drug used for bladder problems, before hip or knee replacement surgery could prevent urinary retention (inability to pee) afterward. 170 men took either tamsulosin or a placebo for five days before and two days after surgery. The main goal was to see if fewer men in the tamsulosin group needed a catheter within 48 hours after the operation.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
tamsulosin
What this could lead to
If it works, this could offer a simple way to prevent a common complication after joint replacement surgery.
What could go wrong
This is a small, completed Phase 4 trial. The drug may not reduce retention risk significantly, and it can cause side effects like dizziness or low blood pressure.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 4

Runs after approval, following long-term safety and how well the treatment works in everyday use.

Participants

170 people

The number who actually took part.

Started

Aug 2019

Finished

Mar 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Male participants only

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: \- male adults undergoing elective hip- or knee arthroplasty Exclusion Criteria: * women * underage patients * pre-existing treatment with tamsulosin or other prostate affecting medication * patients who underwent transurethral resection of the prostate or prostatectomy * patients with urethral strictures * patients with neurological bladder dysfunction * Known allergy to tamsulosin * Hypotensive disorder

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Conditions

The condition(s) this trial relates to.

osteoarthritis, hip osteoarthritis, knee Urinary Retention

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Arthropathy of hip Arthropathy of knee Urinary retention postoperative

Contacts and locations

Locations

  • Kantonsspital Graubünden

    Chur, Kanton Graubünden, 7000, Switzerland

More trials for these conditions

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