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Which nerve block gets knee patients moving faster?

NCT ID NCT07442123

Symptom relief Sponsor: Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looked at 90 adults having knee replacement surgery to see which nerve block technique works better for pain control and getting patients moving sooner. One group got a fascia iliaca plane block, the other got a combination of adductor canal and IPACK blocks. Researchers measured pain, opioid use, and how early patients could walk.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
bupivacaine
What this could lead to
If this study shows one nerve block works better, it could help patients recover faster with less pain after knee replacement.
What could go wrong
This is a small observational study, not a large trial. Results may not apply to all patients, and individual responses to nerve blocks can vary.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

90 people

The number who actually took part.

Started

Dec 2022

Finished

Jan 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

The study population consists of adult patients undergoing elective unilateral total knee arthroplasty at a tertiary care hospital. Eligible participants include patients receiving spinal anesthesia and perioperative peripheral nerve block analgesia as part of routine clinical practice. The population represents individuals undergoing primary knee replacement surgery for degenerative joint disease who are suitable for early postoperative mobilization and standardized postoperative pain management protocols.

Ages

18 to 80 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adult patients aged 18-80 years * Scheduled for elective unilateral total knee arthroplasty * Surgery performed under spinal anesthesia * American Society of Anesthesiologists (ASA) physical status I-III * Ability to understand the study procedures and provide informed consent Exclusion Criteria: * Refusal to participate * Contraindications to spinal anesthesia or peripheral nerve block * Known allergy to local anesthetics * Chronic opioid use or opioid dependence * Preexisting neurological or neuromuscular disorders affecting lower extremities * Cognitive impairment preventing pain assessment * Infection at the injection site * Coagulopathy or ongoing anticoagulant therapy contraindicating regional anesthesia

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Conditions

The condition(s) this trial relates to.

agnosia osteoarthritis susceptibility 6 osteoarthritis, knee Pain, Postoperative

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Arthropathy of knee Early ambulation Pain management Pain, postoperative

Contacts and locations

Locations

  • SBU Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital

    Ankara, 06200, Turkey (Türkiye)

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