ARTERIAL STIFFNESS

This study looks at whether eating grapes every day can improve gut health, reduce inflammation, and help blood vessels work better in overweight adults aged 45 to 70. Participants will drink grape powder or a placebo twice daily for three weeks. Researchers will measure changes …

This study tests whether a daily dose of freeze-dried wild blueberry powder can improve blood sugar, blood pressure, thinking skills, and gut bacteria in women aged 20-65 who have prediabetes and are overweight. Participants will take the powder for a set period while researchers…

This study looks at whether eating wild blueberries can improve heart health, thinking skills, and gut bacteria in Black and White adults aged 45-65 with high blood pressure. Participants will eat blueberries and have their blood pressure, artery stiffness, and memory tested. The…

This study tests whether dapagliflozin, a drug used for diabetes, can prevent heart damage caused by a common type of chemotherapy (anthracycline) in women with breast cancer. About 100 participants will take either dapagliflozin or a placebo daily during their chemo. Researchers…

This study tests whether a daily pill called empagliflozin (a type of SGLT2 inhibitor) can reduce stiffening of arteries that happens with age. The trial will include 80 healthy adults aged 60-80 who have some artery stiffness but no diabetes. Participants will take the drug or a…

This study looks at whether upper arm aerobic exercise can reduce stiffness in the arteries caused by breast cancer treatments like chemotherapy. Researchers will measure artery health in 18 women aged 40-69 who are at least 15 months past breast cancer surgery. The goal is to se…

This study tests whether taking vitamin K2 supplements for 6 months can lower the number of migraine days per month in adults with episodic migraine. Researchers will also check if it improves artery stiffness, which is often higher in people with migraines. About 160 participant…

This study looks at how a specific blood fat called lipoprotein(a) affects the stiffness of arteries, the health of blood vessel linings, and the heart's ability to pump. Researchers will follow 300 adults for one year, measuring these factors and tracking any heart problems. The…

This study follows 155 adults with CADASIL, a genetic condition that narrows small blood vessels and can cause strokes and dementia, over 9 years. Researchers will track changes in blood vessels, brain scans, and thinking abilities through four visits. The goal is to learn how th…

This study looks at how testosterone and estrogen therapy changes metabolism, eating habits, and heart health in transgender individuals. Researchers will measure energy use, insulin sensitivity, and artery stiffness in 80 participants over time. The goal is to understand how sex…

This study follows 7,500 adults over 12 to 16 years to see how their arteries change with age and how that affects their risk of heart disease and stroke. Researchers will use advanced ultrasound to measure artery stiffness and thickness. No treatments or drugs are given—the goal…

This study looks at how blood pressure and artery stiffness change between day and night in 120 people at increased risk for heart disease, including those with kidney issues. Researchers want to understand who lacks the healthy nighttime blood pressure drop and whether taking me…