New study probes hidden heart risk from common blood fat
NCT ID NCT07324902
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at how a type of fat in the blood called lipoprotein(a), or Lp(a), affects the stiffness of arteries, the health of blood vessel linings, and the heart's ability to pump. Researchers will follow 300 adults for one year, measuring these factors and tracking heart attacks, strokes, or heart-related deaths. The goal is to better understand the risks linked to high Lp(a) levels.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this study could clarify how high Lp(a) damages blood vessels and the heart, pointing toward better risk assessment or future treatments.
- What could go wrong
- This is an observational study, not a treatment trial. It cannot prove cause and effect, and results may not apply to all populations.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 300 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Sep 2024
- Expected to finish
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Aug 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
This observational study will include adults aged 18-75 years (regardless of gender) who visit the outpatient clinics of the 2nd University Cardiology Clinic at "Attikon" General Hospital. All participants will sign a consent form. A full medical history, clinical examination, and blood collection will be performed to determine levels of Total Cholesterol, LDL-C, HDL-C, triglycerides, and Lp(a) at each visit. Participants will be divided into three groups: * Group A: Lp(a) ≥50 mg/dL with Total Cholesterol\<200 mg/dl * Group B : Lp(a) \<50 mg/dL. with Total Cholesterol\>200 mg/dl * Group C (Control): Lp(a) \<50 mg/dL. with Total Cholesterol\<200 mg/dl At each group n ≥ 100 participants are anticipated.
- Ages
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18 to 75 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Adults participants 18-75 years old * Willing to sign the informed consent and paerticipate in the study Exclusion Criteria: * History of autoimmune/autoinflammatory disease, * Severe valvular heart disease, * severe chronic kidney disease(eGFR\<60 ml/min/1.73 m2), * Active Pregnancy * Severe hepatic impairment.
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Genom att skicka in godkänner du våra Användarvillkor
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
2 sites. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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"Attikon" University General Hospital
RECRUITINGAthens, Attica, 12462, Greece
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Attikon University Hospital, 2nd Department of Cardiology, National and Kapodistrina University of Athens
RECRUITINGAthens, Rimini 1, 12462, Greece
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