ANTERIOR CRUCIATE LIGAMENT INJURIES

This study compares two common tendon grafts used in ACL reconstruction surgery: the semitendinosus (hamstring) and the quadriceps tendon. Researchers want to see which one leads to better knee stability and function after surgery. About 200 people with ACL tears who plan to retu…

This study compares two surgical methods for fixing a torn ACL, the main knee ligament. Forty adults will be randomly assigned to receive either a single-bundle or double-bundle reconstruction, both combined with an extra ligament repair. Researchers will track knee stability, fu…

This study tests whether a concentrated bone marrow injection (cBMA) given during revision ACL surgery can reduce knee pain and inflammation from post-traumatic osteoarthritis. About 40 adults aged 18-55 who need a second ACL repair will be randomly assigned to get cBMA or not. R…

This study compares two different tendon grafts used to repair a torn ACL in the knee: one from the hamstring and one from a leg muscle called peroneus longus. Sixty adults with an isolated ACL tear will be randomly assigned to receive one of the grafts during arthroscopic surger…

This study tests whether a platelet-rich plasma (PRP) injection given soon after an ACL tear can reduce inflammation and improve knee function, with the goal of lowering the risk of post-traumatic osteoarthritis later. About 56 people with a recent ACL injury will receive either …

This study tests a new type of MRI scanner that may show knee ligaments and tendons more clearly than standard MRI. Researchers will scan 20 adults who are already scheduled for ligament repair surgery to see if the new method can accurately detect ACL tears and other injuries. T…

This study tests whether injecting a drug called anakinra into the knee soon after an ACL injury can prevent arthritis from developing years later. About 32 people aged 18 to 35 with a confirmed ACL tear will receive either the drug or a placebo. Researchers will track pain, func…

This study tests a wearable electrical stimulation knee sleeve (KneeStim) in 60 military cadets aged 17-27 recovering from ACL reconstruction. Participants wear the device during rehab and daily tasks for 12 weeks. Researchers compare standard rehab plus low-intensity stimulation…

This study tests whether adding balance exercises to standard rehab after ACL surgery improves balance, reduces fear of movement, and boosts daily function. About 50 adults who had ACL surgery will be split into two groups: one gets standard rehab, the other adds balance exercise…

This study looks at whether wearing a brace after ACL reconstruction helps people feel more confident and ready to return to sports. Researchers will compare people who wear a brace to those who don't. The goal is to see if bracing improves psychological readiness and reduces fea…

This study tests whether a program combining graded exposure (slowly facing feared movements) and mindfulness meditation can help people who had ACL knee surgery feel less afraid of re-injury. About 50 participants, aged 14 to 35, who had surgery 6 months to 10 years ago will be …

This study tests whether giving morphine directly into the bone during ACL reconstruction surgery can lower pain and reduce the need for opioid painkillers afterward. About 84 adults aged 18 to 40 having ACL surgery with a specific type of graft will take part. Participants will …

This study tests whether whole-body vibration therapy can reduce knee pain in people who still have pain after ACL reconstruction surgery. Researchers will enroll 50 adults aged 18 to 60 who have had a single ACL repair and have ongoing kneecap pain. Participants will use a vibra…

This study looks at whether adding blood flow restriction training (BFRT) to standard physical therapy helps teenagers recover leg strength and muscle size after ACL knee surgery. About 40 teens who had ACL reconstruction will be randomly assigned to either standard rehab or stan…

This study looks at whether a special balance training program using visual feedback can help people recover knee function and walking ability after ACL reconstruction. About 45 patients who had ACL surgery will be compared to healthy volunteers. The goal is to see if this traini…

This study looks at how many steps people take each day after ACL knee surgery and whether that affects their knee cartilage health. Researchers will use MRI scans to measure cartilage changes in 56 participants. The goal is to understand if walking more can help prevent osteoart…

This study tests whether a robot can help surgeons place bone tunnels more accurately during ACL knee reconstruction. About 30 people aged 10 to 45 who need ACL surgery will take part. The robot guides the drilling of the tunnels, and the team checks accuracy by comparing planned…

This study follows 500 people who are already scheduled for minimally invasive shoulder or knee surgery for sports injuries like torn ligaments or rotator cuff tears. Researchers will track their recovery for two years using questionnaires about pain and function. The goal is to …

This study aims to build a database of normal movement patterns in healthy athletes aged 10 to 65. Researchers will track participants for 12 months to see who gets injured, especially ACL injuries. The goal is to better understand injury risk factors, not to test a treatment.

This study looks at whether having a stiff knee (unable to fully straighten) soon after ACL surgery affects how well the thigh muscles recover strength. Researchers will compare two groups of 30 patients: those with a knee extension deficit greater than 5 degrees and those withou…