ANEURYSMAL SUBARACHNOID HEMORRHAGE

This study tests whether injecting the drug nicardipine directly into the spinal fluid can improve recovery in people who develop blood vessel spasms after a brain aneurysm rupture. About 396 adults who have had a brain aneurysm treated and a drain placed will be randomly assigne…

This study tests a drug called deferoxamine in people who have had a type of bleeding stroke (aneurysmal subarachnoid hemorrhage). The drug works by removing extra iron that can harm the brain after the bleed. About 120 participants will receive either the drug or a placebo, and …

This study tests whether a drug called tocilizumab-aazg is safe for people who have had a burst brain aneurysm. The goal is to see if it can also help prevent strokes that sometimes happen after the initial bleeding. The study will include 30 adults and focuses on safety and side…

This study tests whether a medicine called fludrocortisone can help people recover better after a serious brain bleed from a burst aneurysm. About 524 adults in intensive care will receive either the drug or a placebo. The goal is to see if the drug reduces death and long-term di…

This study is a large registry that will collect information from 1,000 people treated for brain aneurysms or stroke using MicroVention devices. The goal is to see how well these treatments work in real-life settings, such as how completely aneurysms are closed or how well blood …

This study is looking at 2000 people who have had a brain aneurysm rupture (aSAH) to understand why some recover well and others have serious complications. Researchers will collect blood, spinal fluid, urine, and other samples to study genes, proteins, and other molecules. The g…

This study looks at a new way to treat severe brain bleeds caused by an aneurysm. Doctors will only coil the bulging part of the aneurysm, not the neck. The goal is to see if this method reduces the risk of another bleed and improves recovery. About 30 adults with severe bleeds w…