ANATOMIC STAGE IV BREAST CANCER AJCC V8
Clinical trials for ANATOMIC STAGE IV BREAST CANCER AJCC V8 explained in plain language.
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Promising combo for rare breast cancer stalls after single patient
Disease control TerminatedThis early-phase study aimed to find the best dose and test the safety of combining two drugs—dasatinib and icosapent ethyl—for people with a rare, aggressive breast cancer that had spread. Only one person enrolled before the study was stopped early, so no conclusions about effec…
Matched conditions: ANATOMIC STAGE IV BREAST CANCER AJCC V8
Phase: PHASE1, PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated May 26, 2026 08:03 UTC
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Brain cancer study halted: new radiation methods tested for recurrent tumors
Disease control TerminatedThis study looked at two ways to treat cancer that has spread to the brain and returned after initial radiation. One method used focused radiation only on the new tumors, while the other used whole-brain radiation while trying to protect memory areas and adding a medication to re…
Matched conditions: ANATOMIC STAGE IV BREAST CANCER AJCC V8
Phase: PHASE3 • Sponsor: NRG Oncology • Aim: Disease control
Last updated May 22, 2026 14:01 UTC
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New drug cocktails aim to shrink Hard-to-Treat breast tumors
Disease control TerminatedThis study tested several drug combinations in 24 people with metastatic triple-negative breast cancer, a type that has spread and is tough to treat. The drugs work by blocking cancer growth signals or boosting the immune system. The study was stopped early, so results are limite…
Matched conditions: ANATOMIC STAGE IV BREAST CANCER AJCC V8
Phase: PHASE2 • Sponsor: Gordon Mills, MD, PhD • Aim: Disease control
Last updated May 22, 2026 13:52 UTC
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Cancer brain metastasis drug combo trial halted early
Disease control TerminatedThis study tested two drugs, bintrafusp alfa and pimasertib, in people whose cancer had spread to the brain. The goal was to find the best dose and see if the combination could slow or stop tumor growth. The trial was stopped early after enrolling only 8 participants, so no clear…
Matched conditions: ANATOMIC STAGE IV BREAST CANCER AJCC V8
Phase: PHASE1, PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated May 15, 2026 11:55 UTC
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New combo therapy for rare breast cancer mutation shows promise in early trial
Disease control TerminatedThis study looked at adding a targeted drug (binimetinib) to standard hormone therapy (fulvestrant) for people with a certain genetic change (NF1) in advanced breast cancer. The goal was to see if the combination could shrink tumors or keep them from growing longer than the stand…
Matched conditions: ANATOMIC STAGE IV BREAST CANCER AJCC V8
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated May 13, 2026 16:01 UTC
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Promising combo trial for aggressive breast cancer halted early
Disease control TerminatedThis study looked at adding a drug called copanlisib to standard targeted therapy (trastuzumab and pertuzumab) for people with advanced HER2-positive breast cancer that has a specific genetic change (PIK3CA or PTEN mutation). The goal was to see if the combination could shrink tu…
Matched conditions: ANATOMIC STAGE IV BREAST CANCER AJCC V8
Phase: PHASE1, PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated May 11, 2026 20:38 UTC
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Can meal timing protect your brain during cancer radiation?
Symptom relief TerminatedThis study tested a mobile app that helps people with brain metastases from breast or lung cancer follow a time-restricted eating plan (eating only during certain hours). The goal was to see if this approach could reduce memory and thinking problems after stereotactic radiosurger…
Matched conditions: ANATOMIC STAGE IV BREAST CANCER AJCC V8
Phase: NA • Sponsor: Thomas Jefferson University • Aim: Symptom relief
Last updated May 22, 2026 14:01 UTC
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Cancer trial uses DNA tests to pick drugs, but stops early
Knowledge-focused TerminatedThis study tested a precision medicine approach for people with advanced cancers like breast, prostate, or pancreatic cancer. Researchers used genetic and protein tests to track how each person's cancer changed over time, then a team of experts recommended personalized drugs. The…
Matched conditions: ANATOMIC STAGE IV BREAST CANCER AJCC V8
Phase: PHASE2 • Sponsor: OHSU Knight Cancer Institute • Aim: Knowledge-focused
Last updated May 26, 2026 07:54 UTC
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Antifungal drug studied for brain tumor treatment
Knowledge-focused TerminatedThis early-stage study looked at whether ketoconazole, an antifungal drug, could block a protein called tGLI1 in brain tumors. The study included 15 people with either breast cancer that spread to the brain or a type of brain tumor called glioma. The goal was to see if the drug c…
Matched conditions: ANATOMIC STAGE IV BREAST CANCER AJCC V8
Phase: EARLY_PHASE1 • Sponsor: Wake Forest University Health Sciences • Aim: Knowledge-focused
Last updated May 26, 2026 07:25 UTC