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Promising combo for inflammatory breast cancer stalls after single patient

NCT ID NCT05198843

First seen Nov 01, 2025 · Last updated Jun 22, 2026 · Updated 29 times

Summary

This early-phase trial tested a combination of two drugs—icosapent ethyl (an omega-3 fatty acid) and dasatinib (a targeted cancer drug)—in people with a rare, aggressive form of breast cancer that had spread. The goal was to find a safe dose and see if the combo could shrink tumors. However, the study was stopped early after only one person enrolled, so we have no useful information about whether the treatment works.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • M D Anderson Cancer Center

    Houston, Texas, 77030, United States

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

icosapent ethyl (an omega-3 fatty acid) and dasatinib (a targeted cancer drug)

What this could lead to

If it had worked, this combination might have pointed toward a new treatment option for a very aggressive breast cancer.

What could go wrong

The trial was terminated after enrolling only 1 person, so no meaningful conclusions can be drawn. It is too early to know if this combination is safe or effective.

Conditions

The condition(s) this trial relates to.

breast cancer triple-negative breast carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.