ALCOHOL DRINKING

This study tests different ways to help people scheduled for major elective surgery drink less alcohol before and after their operation. The goal is to improve surgical recovery and long-term health. About 440 adults who drink at risky levels will receive personalized support thr…

This study looks at whether a brief counseling session can help injured patients who drink heavily change their habits. Researchers will track 830 adults admitted to the hospital for injuries to see if the talk reduces repeat hospital visits, DUIs, and risky drinking. The goal is…

This study tests whether online mindfulness classes help people with alcohol use disorder stay in recovery longer than online support groups. About 470 adults who recently tried to cut back or stop drinking will take part. The goal is to see if mindfulness helps people avoid heav…

This study tests a program called Journey of Transformation for Native youth in tenth grade at an off-reservation boarding school. The goal is to see if it can delay or reduce tobacco, alcohol, and other drug use, and improve sexual health. About 182 participants will be followed…

This study tests whether adding trauma coping strategies and peer coaches to a standard mobile alcohol intervention helps young adults (ages 18-25) who have experienced interpersonal trauma reduce heavy drinking. 225 college students are randomly assigned to the enhanced program,…

This study tests a telephone-based, computer-aided care program for adults with depression, anxiety, or risky drinking. Participants receive extra support from a Mental Health Technician who helps their primary care provider manage treatment. The goal is to see if this approach r…

This study looks at how a single dose of a ketone ester supplement changes glucose use in the brain and heart of people with and without alcohol use disorder. Researchers will use PET/CT scans to measure these effects in 20 participants (10 with alcohol use disorder and 10 health…

This study looks at how being in ketosis (a state where your body burns fat for energy) affects the way your body processes alcohol and how your brain works. Healthy adults will follow three different 3-day diets and then drink about 4-5 alcoholic beverages. Researchers will use …

This study looks at whether taking a ketone supplement before drinking alcohol changes how drunk people feel or how alcohol shows up in their breath or blood. Ten healthy volunteers each visit the lab twice, once getting the supplement and once getting a placebo, then drink a sma…

This study looks at how alcohol changes the way our brains work together during social situations. Researchers will monitor brain activity in pairs of people while they drink and interact. The goal is to understand the brain mechanisms behind alcohol's social effects. 240 regular…

This study aimed to see if adding trauma coping strategies and peer coaching to a mobile alcohol program helps young adults (ages 18-29) with past interpersonal trauma drink less. Participants would have been randomly assigned to the enhanced program or standard version and follo…

This study is developing a program called mSTARS for people who drink heavily and have been hospitalized for a suicide crisis. The program combines in-hospital skills training with a smartphone app to help manage emotions after discharge. Ten participants will test the program an…

This study planned to test a digital health worker named PAHOLA that would deliver counseling to people who drink too much alcohol but face barriers to getting treatment. The goal was to see if talking to a computer-based helper could reduce drinking and improve health. However, …