ACUTE MYOCARDIAL INFARCTION

This study tests whether giving the drug adenosine before angioplasty (a procedure to open blocked heart arteries) can reduce the risk of slow or no blood flow afterward in people having a heart attack. About 1,148 adults with a specific type of heart attack (STEMI) will take par…

This study looks at whether treating severe gum disease (periodontitis) can reduce inflammation in the arteries of people who have had a heart attack. About 210 participants will receive either specialized gum treatment or standard dental care. The main goal is to see if gum trea…

This study tests whether getting a flu vaccine outside of flu season can reduce inflammation in the arteries of people who recently had a heart attack. About 90 participants will receive either the flu vaccine or a placebo, and doctors will use special CT scans to measure artery …

This study tests whether a single injection of morphine around certain neck nerves can reduce heart muscle damage in people who have had a heart attack and undergone a procedure to open blocked arteries. Researchers will compare the morphine injection to a placebo (salt water) in…

This study tests whether giving a special oxygen-rich treatment for 60 minutes right after standard artery-opening angioplasty can reduce heart damage and complications in people having a large front-wall heart attack. About 434 participants will be randomly assigned to receive e…

This study tests whether a non-invasive treatment called remote ischemic preconditioning (RIPC) can reduce the risk of major heart and brain events in people who have had a heart attack. About 2,146 participants will use a blood pressure cuff on their arm to briefly restrict bloo…

This study follows 100 people who had a heart attack and received the cell therapy Hearticellgram-AMI. Researchers are monitoring for serious side effects such as death, new cancers, or immune reactions over the long term. The goal is to ensure the treatment remains safe after it…

This study tests whether giving a cholesterol-lowering drug (PCSK9 inhibitor) right after a heart attack can help save more heart muscle compared to standard care. About 160 adults having a severe heart attack will be randomly assigned to get the drug or usual treatment. The main…

This study tests a new approach to blood thinners for people who have had a heart attack. The goal is to see if using a lower dose of the drug ticagrelor and stopping aspirin early can reduce the risk of dangerous bleeding while still preventing another heart attack or stroke. Ab…

This study follows 774 adults who develop a new type of irregular heartbeat (atrial fibrillation) while in the hospital after a heart attack. Researchers want to understand how serious this condition is and find better ways to predict risks and guide blood-thinner treatment. Part…

This study follows 15,000 people who survived a heart attack and were part of an earlier project. Researchers will call them at 3 and 5 years after leaving the hospital to check their health, medications, and whether they had serious heart problems like another heart attack, stro…

This study looks at how common mild depression is in people who have had their first heart attack. Researchers will follow 100 patients for a year to see if these mild symptoms affect recovery, heart health, and quality of life. The goal is to better understand the connection bet…

This study looks at how different types of aerobic exercise affect blood vessel health in people with heart disease. Researchers will compare high-intensity interval training (with long or short bursts) to moderate-intensity training. 132 adults aged 45-75 who had a heart event o…

This study is not testing a new drug or device. Instead, it will track 500 people with cardiogenic shock (a life-threatening condition where the heart suddenly can't pump enough blood) at four specialized hospitals. Researchers will collect detailed information on treatments and …