ACUTE ISCHEMIC STROKE

This study tests a special stent (CGuard Prime) placed in the neck artery to treat acute ischemic stroke. It involves 15 adults with a blocked large brain artery and at least moderate stroke symptoms. The goal is to see if the stent is safe and helps patients recover with less di…

This study offered an experimental treatment using donor stem cells given through an IV to people who had a recent (within 9 days) ischemic stroke. The goal was to see if the stem cells could help the brain heal and improve recovery. It was available to adults aged 18 to 80 with …

This study tests whether adding the steroid methylprednisolone to standard clot-removal treatment helps people with severe strokes live longer and recover better. About 928 adults with large brain clots will receive either the drug or a placebo within 12 hours of stroke onset. Th…

This study planned to test whether the antibiotic minocycline could improve recovery in people who had a severe stroke and received a procedure to remove the clot. Participants would have taken minocycline or a placebo for 21 days. However, the study was withdrawn before enrollin…

This study tests whether infusing a cold magnesium sulfate solution directly into the brain artery after clot removal can improve recovery in people with severe stroke. About 42 adults aged 18-80 with a large vessel blockage in the front part of the brain will be enrolled. The go…

This study tests an investigational drug called redasemtide in 680 adults who recently had a stroke caused by a blood clot. Participants receive either the drug or a placebo within 25 hours of their stroke. The main goal is to see if the drug helps improve recovery and daily func…

This study was designed to test a device that removes blood clots in the brain during a stroke. It was withdrawn before any participants were enrolled, so no results or safety information are available. The device is meant to restore blood flow in people having a severe stroke ca…

This study tests whether a structured exercise program done at home can improve walking ability and daily function in people who recently had a stroke. About 208 adults who had a stroke within the past two weeks will take part. The goal is to see if this safe, convenient approach…

This study planned to test a device called the SOFIA Flow 88 Aspiration Catheter for removing blood clots in people having a severe stroke. The goal was to see if it could safely restore blood flow to the brain. However, the study was withdrawn before enrolling any participants, …

This study compares a minimally invasive procedure (endovascular treatment) to standard care for 300 adults aged 18-80 who have had a mild stroke caused by a blocked large artery in the front part of the brain. Participants must be treated within 24 hours of symptoms starting. Th…

This study tests if giving the clot-busting drug tenecteplase directly into the brain artery after mechanical clot removal is safe and helps people with severe stroke. About 40 adults who had a large-vessel blockage stroke within the last 4.5 to 24 hours will receive the drug dur…

This study compares two types of brain scans — PET and CT — in 20 adults who recently had a stroke. The goal is to see how well PET measures blood flow and brain metabolism compared to standard CT scans. Participants get both scans within a week of their stroke, and some may have…