Somatoform disorder
MONDO:0003117A category of psychiatric disorders which are characterized by the presence of physical symptoms that suggest a medical condition but are not fully explained by any known medical reasons.
Also known as: somatoform disorder, physiological malfunction arising from mental factor, psychophysiologic disorder, psychosomatic disorder
127 clinical trials for this condition and its sub-types, 47 tagged with Somatoform disorder itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
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Sub-types of Somatoform disorder
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Conversion disorder 48 trials
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Somatization disorder 21 trials
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Body dysmorphic disorder 19 trials · 20 incl. sub-types
1 sub-type
- Muscle dysmorphic disorder 1 trial
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Hypochondriasis 12 trials
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Neurocirculatory asthenia 1 trial
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Could your phone replace a $1,000 Back-Flexibility device?
Diagnosis CompletedThis study compares a smartphone app (iPhone Level) to a specialized device (BROM) for measuring how much the lower back can bend forward, backward, and sideways. Researchers will enroll 120 healthy male university students aged 18–25 with normal body weight. If the app works wel…
Sponsor: Cairo University • Aim: Diagnosis
Last updated Jul 04, 2026 00:00 UTC
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New checklist could help heart patients get the right diagnosis
Diagnosis CompletedThis study tested a new questionnaire called SSS-CN to see if it can accurately detect somatic symptom disorder (physical discomfort with no clear medical cause) in heart clinic patients. Over 1,800 adults aged 18-80 who had no diagnosed physical illness completed the checklist a…
Sponsor: RenJi Hospital • Aim: Diagnosis
Last updated Jun 27, 2026 07:52 UTC
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Electric suit aims to ease spasticity and boost balance in kids with cerebral palsy
Symptom relief CompletedThis trial tests whether a wearable suit called EXOPULSE Mollii, which sends gentle electrical pulses to muscles, can help children with cerebral palsy. The study focuses on kids aged 5 to 12 who have spasticity and some walking ability. Researchers will measure changes in balanc…
Sponsor: Exoneural Network AB • Aim: Symptom relief
Last updated Aug 07, 2026 00:00 UTC
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Can a therapist's virtual hand-holding make online therapy for unexplained symptoms more effective?
Symptom relief CompletedThis trial compares two versions of an internet-based emotional awareness and expression therapy (I-EAET) for people with functional somatic disorder—a condition where physical symptoms like chronic pain or fatigue have no clear medical cause. One group gets weekly written feedba…
Sponsor: Daniel Maroti • Aim: Symptom relief
Last updated Jul 29, 2026 00:00 UTC
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Talking about emotions may ease unexplained pain — a trial puts it to the test
Symptom relief CompletedThis trial compares two types of first interviews for people with functional somatic disorders — conditions like irritable bowel syndrome or fibromyalgia where physical symptoms have no clear medical cause. One interview focuses on life stress and emotional factors, while the oth…
Sponsor: Daniel Maroti • Aim: Symptom relief
Last updated Jul 29, 2026 00:00 UTC
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Talking through the pain: could uncovering hidden emotions relieve chronic symptoms?
Symptom relief CompletedThis trial tests whether a short-term, intensive talk therapy called ISTDP can help people whose physical symptoms—like chronic pain, fatigue, or stomach issues—have not improved with other treatments. The therapy focuses on uncovering and processing unconscious emotions that may…
Sponsor: Daniel Maroti • Aim: Symptom relief
Last updated Jul 29, 2026 00:00 UTC
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Smartphone app could ease chronic pain in advanced cancer patients
Symptom relief CompletedThis study tests a smartphone app called STAMP+CBT that combines pain coping skills training with medication support for people with advanced cancer who have chronic pain. The app provides tailored education and real-time feedback to help users manage their pain. Researchers want…
Sponsor: Dana-Farber Cancer Institute • Aim: Symptom relief
Last updated Jul 10, 2026 00:00 UTC
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Can talk therapy rewire the Brain's body image? a new trial investigates CBT for BDD
Symptom relief CompletedThis study tests whether a specific type of talk therapy called cognitive behavioral therapy (CBT) can help people with body dysmorphic disorder (BDD). Participants receive 22 weekly one-on-one CBT sessions that teach them to challenge negative thoughts and behaviors about their …
Sponsor: Massachusetts General Hospital • Aim: Symptom relief
Last updated Jul 04, 2026 00:00 UTC
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Can an online program ease the distress of unexplained physical symptoms?
Symptom relief CompletedThis study tested whether an internet-based exposure therapy program can reduce distress related to physical symptoms better than standard education about healthy lifestyle habits. 161 adults in Stockholm with significant distress from somatic symptoms participated. The treatment…
Sponsor: Region Stockholm • Aim: Symptom relief
Last updated Jun 27, 2026 14:03 UTC
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Can a smartphone app ease mysterious body aches? new study says maybe.
Symptom relief CompletedThis study tested whether a mobile app could help adults with somatic symptom disorder or medically unexplained symptoms. 46 participants used the app for 8 weeks, which taught coping skills like mindfulness and stress management. The goal was to see if symptoms improved compared…
Sponsor: Gangnam Severance Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 13:00 UTC
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Teens with chronic pain try coaching to ease suffering
Symptom relief CompletedThis study tested a resilience coaching program (PRISM) for 260 teens aged 12-17 with chronic musculoskeletal pain. The goal was to see if coaching improves daily function, reduces distress, and lessens pain compared to usual care. Participants completed surveys and coaching sess…
Sponsor: Children's Hospital of Philadelphia • Aim: Symptom relief
Last updated Jun 27, 2026 12:37 UTC
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New hope for HIV nerve pain: Drug-Free relief on the horizon?
Symptom relief CompletedThis study tested new non-drug treatments to reduce nerve pain in the feet and legs of people with HIV. 161 adults with HIV-related nerve pain tried these approaches to see if they could ease pain and improve quality of life. The goal was to find better ways to manage this common…
Sponsor: New York University • Aim: Symptom relief
Last updated Jun 27, 2026 12:35 UTC
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Laser showdown: which light works best for frozen shoulder?
Symptom relief CompletedThis study tested two laser treatments—low-level and high-intensity—in 40 people with frozen shoulder (adhesive capsulitis). The goal was to see which better reduces pain, improves shoulder movement, and boosts daily function over three weeks. Both treatments are non-invasive and…
Sponsor: Necmettin Erbakan University • Aim: Symptom relief
Last updated Jun 27, 2026 12:08 UTC
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Simple muscle relaxation technique shows promise for stressed nursing students
Symptom relief CompletedThis study tested whether progressive muscle relaxation (PMR) — a technique where you tense and then relax different muscle groups — could help nursing students feel less depressed, anxious, and stressed. Over 100 students were split into two groups; one group practiced PMR three…
Sponsor: Ondokuz Mayıs University • Aim: Symptom relief
Last updated Jun 27, 2026 11:00 UTC
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Can medical assistants ease health anxiety? new study says yes
Symptom relief CompletedThis study tested a short, four-session therapy program for people who worry excessively about their health. Medical assistants delivered the therapy in primary care clinics. 68 adults took part, and the study measured changes in health anxiety over 12 weeks. The goal was to see …
Sponsor: Dartmouth-Hitchcock Medical Center • Aim: Symptom relief
Last updated Jun 27, 2026 09:01 UTC
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Group therapy shows promise for teens battling anxiety and depression
Symptom relief CompletedThis study tested a group version of a therapy program called the Unified Protocol for teens with emotional disorders like anxiety and depression. Thirty-one adolescents took part in 16 weekly group sessions at a public mental health center in Spain, along with three parent sessi…
Sponsor: Universidad Nacional de Educación a Distancia • Aim: Symptom relief
Last updated Jun 26, 2026 17:39 UTC
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Can smartphones replace In-Person therapy during a pandemic?
Knowledge-focused CompletedThis study looked at whether digital services like smartphone apps can help people with psychosomatic disorders continue their treatment during the COVID-19 pandemic, when social distancing and hygiene rules limit in-person therapy. About 2000 patients from clinics took part, usi…
Sponsor: Jacobs University Bremen gGmbH • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:07 UTC
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New program aims to help Long-COVID patients with online screening and personal support
Knowledge-focused CompletedThis study tested a program for people with long-COVID that includes an online screening, a detailed in-person assessment, and digital training modules with a personal counselor. 192 participants from Bavaria took part to see if this approach is practical and helpful. The goal wa…
Sponsor: Prof. Dr. Sonia Lippke • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:07 UTC
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Jaw pain linked to personality and social support in new study
Knowledge-focused CompletedThis study looked at how certain personality traits, physical symptoms without clear cause, and social support relate to temporomandibular joint (TMJ) disorders, which cause jaw pain and difficulty chewing. Researchers compared 90 adults with TMJ disorders to healthy volunteers u…
Sponsor: Gulseren Demir Karakilic • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:07 UTC
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Large study reveals how age affects unexplained physical symptoms
Knowledge-focused CompletedThis study looked at over 9,000 people in China to compare how often older and younger adults experience physical symptoms without a clear medical cause, like pain or fatigue. Researchers used questionnaires to measure these symptoms, along with depression and anxiety. The goal w…
Sponsor: RenJi Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:54 UTC