Serositis

Researchers at a Malaysian hospital reviewed ten years of records for 160 adults who received intrapleural fibrinolytic therapy, a mix of alteplase and DNase delivered through a chest tube, for complicated pleural infection. The study compares how well the treatment cleared fluid…

This study tests whether adding a probiotic (Bifidobacterium quadruple live tablets) to standard antibiotics can better control and prevent the return of spontaneous bacterial peritonitis (SBP) in people with cirrhosis. SBP is a serious infection of the abdominal fluid that often…

This study tests whether ulinastatin, a drug that reduces inflammation, can help patients with severe abdominal infections. The infection often causes the immune system to overreact, leading to organ failure and high risk of death. Researchers will give patients either a low or h…

This pilot study tests whether silver-impregnated dressings can effectively manage catheter exit-site or tunnel infections in adults on peritoneal dialysis. Sixty participants will be randomly assigned to receive either the silver dressing or standard daily antibiotic dressings, …

Peritoneal dialysis uses the belly lining as a natural filter for people with kidney failure, but over time this membrane can scar and stop working. This study tests whether levels of a protein called DKK3 in blood, urine, and dialysis fluid can serve as an early warning sign of …

This study tests whether musculoskeletal ultrasound can reliably detect bone, joint, and soft-tissue problems in adults with blood cancers like leukemia, lymphoma, and multiple myeloma. Participants with symptoms such as bone pain, joint swelling, or muscle pain will receive a de…

This study looks at whether two simple calculations, called Cancer Ratio and Cancer Ratio Plus, can help doctors tell the difference between fluid around the lungs caused by cancer and fluid caused by tuberculosis. These calculations use results from routine blood and fluid tests…

Rheumatoid arthritis and gout can look alike, making them hard to tell apart early. This study will use ultrasound to see if it can reliably distinguish between the two conditions. Researchers will examine 100 adults with suspected or confirmed arthritis, scoring joint inflammati…

This study tests if giving a low-dose norepinephrine drip just before anesthesia can prevent low blood pressure during emergency surgery for a serious belly infection (peritonitis). About 60 adults with stable blood pressure after initial treatment will be randomly assigned to re…

Researchers compare two ways to perform knee surgery for simple problems like meniscal tears, cartilage damage, and loose bodies. One method uses a needle arthroscopy with a 1.9mm camera through tiny openings, and the other uses standard arthroscopy. Adults aged 18 to 65 join the…

This observational study will collect detailed information from 150 adults undergoing emergency surgery for complicated diverticulitis. Researchers will analyze factors that influence surgeons' decisions to perform either a primary anastomosis (reconnecting the bowel) or a Hartma…

This study will collect data from 10,000 patients across Saudi Arabia who undergo emergency abdominal surgery (laparotomy). Researchers will track complications and deaths within 30 and 90 days after surgery. The goal is to understand current care quality, test international risk…

This study will test a new scoring system (Mansoura score) to predict a serious bacterial infection called spontaneous bacterial peritonitis in people with liver cirrhosis and fluid buildup in the belly. Researchers will enroll 250 adults to see how well the score identifies who …

This study looks at fluid from peritoneal dialysis to find biological markers that could signal peritoneal fibrosis, a common complication. Researchers will analyze genetic material and metabolites from 55 participants, including dialysis patients and healthy controls. The goal i…