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Silver dressings could simplify infection care for dialysis patients

NCT ID NCT07641491

Disease control Sponsor: Singapore General Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This pilot study tests whether silver-impregnated dressings can effectively manage catheter exit-site or tunnel infections in adults on peritoneal dialysis. Sixty participants will be randomly assigned to receive either the silver dressing or standard daily antibiotic dressings, alongside systemic antibiotics. The study aims to see if the silver dressing is feasible, acceptable, and reduces the frequency of dressing changes. Results will guide future larger trials.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
silver-impregnated dressing
What this could lead to
If successful, this could offer a simpler, less frequent dressing option for managing catheter infections in dialysis patients, potentially reducing treatment burden.
What could go wrong
This is a small pilot study with only 60 participants, so results may not apply broadly. The dressing may not work as well as standard antibiotics, and some patients may have allergic reactions to silver.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 60 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Jun 2026

An estimate. Start dates often move.

Expected to finish

Mar 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

21 to 90 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adults aged 21 to 90 years * Currently receiving peritoneal dialysis under the Singapore General Hospital Peritoneal Dialysis Programme * Diagnosed with an active catheter exit-site infection or tunnel infection based on standard clinical criteria Exclusion Criteria: * Known allergy or sensitivity to silver dressings * Pregnant * Expected life expectancy of less than 6 months * Unable to provide informed consent * Currently participating in another clinical study involving exit-site care or wound dressings * Planned removal of the peritoneal dialysis catheter within the next 7 days

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Conditions

The condition(s) this trial relates to.

infectious peritonitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Peritoneal dialysis catheter exit site infection Peritoneal dialysis catheter tunnel infection

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Singapore General Hospital

    Singapore, 169608, Singapore

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