Massive saudi study aims to improve emergency surgery survival
NCT ID NCT07429929
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study will collect data from 10,000 patients across Saudi Arabia who undergo emergency abdominal surgery (laparotomy). Researchers will track complications and deaths within 30 and 90 days after surgery. The goal is to understand current care quality, test international risk models, and build a Saudi-specific tool to predict patient outcomes.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this could lead to better surgical care standards and a risk prediction tool tailored for Saudi patients undergoing emergency abdominal surgery.
- What could go wrong
- This is an observational study, not a treatment trial, so it won't directly improve outcomes. Results may not apply outside Saudi Arabia.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 10,000 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Jun 2026
An estimate. Start dates often move.
- Expected to finish
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Dec 2028
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
The study population consists of all eligible patients aged 14 years and older who underwent emergency laparotomy or emergency laparoscopic abdominal surgery at participating hospitals in Saudi Arabia during the defined retrospective audit period. Patients are identified through hospital records and include those operated on for acute intra-abdominal surgical conditions such as gastrointestinal perforation, obstruction, ischemia, bleeding, sepsis, and related emergencies requiring non-elective abdominal surgery. The audit includes consecutive cases meeting predefined inclusion criteria and excludes elective procedures and non-eligible surgical specialties, with data collected retrospectively from routinely documented clinical, operative, and postoperative records.
- Ages
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14 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age ≥14 years * Undergoing an emergency (E1-E4) laparotomy, laparoscopy, or laparoscopically-assisted abdominal operation * Procedures involving the stomach, small bowel, large bowel, or rectum for acute pathology (e.g., perforation, ischemia, abscess, bleeding, or obstruction) * Washout/evacuation of intra-peritoneal abscess or hematoma (excluding those secondary to appendicitis or cholecystitis) * Bowel resection or repair for obstructed/incarcerated hernias with acute presentation (incisional, umbilical, inguinal, femoral) * Adhesiolysis (open or laparoscopic) * Trauma-related emergency abdominal procedures * Inoperable pathology where a definitive operative procedure was intended (not purely diagnostic) * Return to theatre for major wound dehiscence ("burst abdomen") * Complications requiring general surgical intervention following interventional radiology procedures * Complications requiring general surgical intervention following gynecological oncology surgery * Complications following elective or non-elective general/upper GI surgery, where the above criteria are met Exclusion Criteria: * Age \<14 years * Elective laparotomy or laparoscopy * Diagnostic-only laparotomy or laparoscopy (unless abandoned due to inoperable disease) * Appendicectomy or cholecystectomy (including their complications), unless incidental to a more major non-elective gastrointestinal procedure * Non-elective hernia repair without bowel resection or adhesiolysis * Minor wound dehiscence repair (unless bowel resection is required) * Stoma formation via trephine or laparoscopic approach (include only if midline laparotomy is the primary procedure) * Vascular, obstetric, gynecological (except gynecological oncology complications requiring general surgery input), transplant, hepatobiliary, urological, renal, pancreatic, or splenic procedures
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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King Faisal Specialist Hospital & Research Centre
Jeddah, Mecca Region, 23433, Saudi Arabia
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