Postpartum depression

This trial compares two models of doula support for pregnant people on Medicaid in North Central Florida. One group receives enhanced support that starts earlier in pregnancy, happens more often, and continues through the first year after birth. The other group receives standard …

This trial tests whether repetitive transcranial magnetic stimulation (rTMS) can reduce depressive symptoms in women who are pregnant or up to 12 months postpartum. rTMS uses a scalp device to deliver gentle magnetic pulses to a brain area involved in mood, without medication or …

This study explores whether robot-guided repetitive transcranial magnetic stimulation (rTMS) can effectively treat postpartum depression (PPD). Researchers will compare brain activity, heart signals, blood markers, and body awareness in women with PPD versus healthy controls. Par…

This study tests whether doulas can successfully deliver an 8-week program called YouMatter to new or expecting mothers at risk for postpartum depression. The program combines mental health support, parenting tips, and self-care. Forty mothers with mild depression symptoms will p…

This study tests whether adding mental health screening and family planning counseling to routine baby check-ups helps new mothers. About 920 migrant, refugee, and underserved women in Jordan will take part. They will be screened for postpartum depression, receive support or refe…

This study tests whether a nasal spray containing esketamine and dexmedetomidine, given twice after childbirth, can lower the chance of postpartum depression in women who already had mild depressive symptoms during pregnancy. Esketamine is a fast-acting antidepressant, and dexmed…

This trial tests whether a head-mounted device delivering 40 Hz flickering light and pulsed sound can reduce the risk of postpartum depression in women having elective cesarean sections. Participants receive three 30-minute sessions starting after delivery, with a placebo group r…

This trial tests whether a collaborative psychological model—combining daily music listening, a smartphone app with AI chatbot support and mindfulness exercises, telephone check-ins, and wearable monitoring—can reduce the risk of postnatal depression and persistent pain after chi…

This study tests a digital program called 'What Were We Thinking' (WWWT) to prevent postpartum depression and anxiety in first-time mothers in Chile. The program includes short videos, text message prompts, and a virtual group session. Researchers will compare mothers who receive…

This study tests whether a single dose of intranasal dexmedetomidine, given just before labor pain relief, can lower the chance of postpartum depression (PPD). Researchers will enroll 270 women having vaginal deliveries and randomly give them either the drug or a placebo. The mai…

This trial tests whether caregivers reading to their infants in the neonatal intensive care unit (NICU) can steady the baby's heart rate, breathing, and oxygen levels. Researchers will compare these measures in infants whose caregivers read to them against a control group. They w…

This trial tests whether a coordinated care approach—where doulas provide continuous emotional and physical support and nurse-midwives deliver specialized postpartum care—can improve health outcomes for mothers whose babies are born before 34 weeks and admitted to the NICU. Parti…

This pilot trial tests a digital program called Together in Parenting (TIP) designed to help fathers who are experiencing symptoms of depression or anxiety after their child is born. The program includes short podcasts and educational materials based on interpersonal therapy. The…

This trial tests a 12-week, physiotherapist-led online exercise program called POSH-Ex for women who recently gave birth. The program combines pelvic floor training, breathing exercises, and whole-body movements to improve sexual function and overall well-being. Researchers will …

This study tests whether a structured, midwife-led review of the childbirth experience can improve mental health in new mothers and fathers. The intervention involves a 45-60 minute session where parents discuss their birth story, receive emotional support, and get clarifications…

This study investigates whether a single session of whole-body hyperthermia (using an infrared sauna) can quickly improve symptoms of depression and anxiety. Researchers will measure brain activity, inflammation, and mood changes in four groups: healthy postpartum women, postpart…

This study tests a group-based program called the Thinking Healthy Extended Program (THEP) for new mothers with mild to moderate depression. The program is delivered at community health centers in China and aims to improve maternal mental health and child development. Researchers…

This study looks at whether a 6-week program that combines problem-solving therapy with small rewards can help new mothers feel less depressed and drink less alcohol. About 30 mothers who gave birth in the last year will take part. Half will get the program, and the other half wi…

This study tests whether a 3-week bedside yoga program, added to standard depression treatment, can improve mother-infant bonding and reduce depression in new mothers. Fifty-two mothers with perinatal depression will be randomly assigned to yoga plus usual care or usual care alon…

This study will test whether sacral massage (a massage on the lower back) can help reduce pain, depression, stress, and anxiety during labor. About 193 first-time mothers with a single, healthy baby will be randomly assigned to receive the massage or standard care. Researchers wi…

This study tests whether mothers singing lullabies while bathing their newborns can strengthen bonding, reduce postpartum depression symptoms, and boost parenting confidence. About 98 healthy mothers and their full-term babies will take part. Half will bathe their baby three time…

This study tests whether a simple art activity—coloring mandalas—can reduce anxiety and depression in new mothers. Sixty women who recently gave birth will be randomly assigned to either practice mandala coloring at home for eight weeks or receive standard postpartum care. Resear…

This study will test if a program combining supervised exercise and perineal massage during pregnancy can help prevent problems like urinary incontinence, depression, and gestational diabetes. About 2000 healthy pregnant women will be randomly assigned to either the program or us…

This pilot study tests whether a one-day online cognitive behavioral therapy (CBT) workshop can help women with postpartum depression in Türkiye. Sixty mothers with depressive symptoms will be randomly assigned to either the workshop or usual care. The study focuses on whether th…

This study will test whether video-guided mindfulness exercises can help reduce depression symptoms and improve quality of life in 120 pregnant women in Ethiopia. Participants will attend a health center three times a week for eight weeks to listen to guided mindfulness sessions.…

Researchers at Sheba Medical Center are testing whether AI-generated medical summaries help pregnant patients hospitalized for high-risk pregnancies feel more informed and involved in their care. Half of the 200 participants receive up to three AI-written summaries of their medic…

This study explores whether wearable devices like the Oura Ring and EmbracePlus watch can help track mood changes during pregnancy and after birth. Ten pregnant individuals with a history of major depressive disorder will wear a device daily from the third trimester to three mont…

This study compares screening for postpartum depression at 2 weeks after birth versus the usual 6-8 weeks. Researchers will randomly assign 428 new mothers to either early or routine screening using a simple questionnaire. The goal is to see if earlier screening helps identify de…

This observational study will follow 140 women after vaginal delivery to see if using epidural pain relief during labor is linked to better postpartum recovery and mother-infant bonding. Researchers will use questionnaires to measure recovery quality and bonding in the first day …

This study will survey 385 women who gave birth within the past 4 weeks to 12 months to understand how often postpartum depression occurs and how it relates to body image dissatisfaction, self-objectification, and comparing appearances on social media. Participants answer online …

This study looks at whether recommending bed rest to pregnant women with a short cervix actually helps prevent preterm birth. Researchers will compare women who are told to rest with those who continue normal daily activities. The goal is to see if avoiding bed rest is just as sa…

This study looks at whether video or phone calls with a breastfeeding counselor can help first-time mothers breastfeed longer, feel more confident, and have fewer symptoms of postpartum depression. About 100 new moms will either get standard care or extra telehealth support. The …

This study will test whether training nurses and midwives in respectful maternity care and using a structured action plan can improve outcomes for mothers and newborns after birth. Researchers will compare women who receive standard care with those who receive care after the trai…