Osteoarthritis, hand

This trial compares two surgical procedures for thumb arthritis at the base of the thumb. One is a newer technique called Mini TightRope suspensionplasty, which uses a small suture-button system to stabilize the joint. The other is the standard ligament reconstruction and tendon …

This phase 3 trial tested whether methotrexate, a drug used for other types of arthritis, can reduce pain and improve quality of life in people with erosive hand osteoarthritis. 64 participants received either methotrexate or a placebo once a week for 12 months. The study measure…

This early-stage trial tested a new injection for wrist osteoarthritis that combines the patient's own fat (microfat) and platelet-rich plasma (PRP). The goal was to see if this mixture is safe and can reduce pain and improve wrist function, potentially delaying the need for surg…

This study looks at whether a 12-week digital program—featuring guided exercises, educational lessons, and physiotherapist support—can reduce pain and improve function in people with hand osteoarthritis. Participants use the program at home and report their pain, hand function, a…

This study compares two common surgeries for thumb arthritis: total joint replacement (arthroplasty) and trapeziectomy (removing a small bone). Researchers will analyze data from 1,000 patients aged 45 and older in a Swedish registry, tracking pain, function, and complications fo…

This study compared two surgeries for severe thumb arthritis: simple removal of a small wrist bone (trapeziectomy) versus removal plus ligament reconstruction (the Weilby procedure). Sixty patients were randomly assigned to one surgery. The goal was to see which provides better p…

This study tested whether a steroid injection into the thumb joint can reduce pain and improve hand function in people with thumb osteoarthritis. 61 adults received either a steroid shot or a placebo (salt water) and were followed for 6 months. The goal was to see if the steroid …

This study looked at whether a mix of two common injections—cortisone and hyaluronic acid—works better than cortisone alone for thumb arthritis pain. 150 adults with moderate to severe pain took part. The goal was to see if the combination provides more relief.

This study looked at whether strengthening a small thumb muscle (the first dorsal interosseous) can help people with thumb arthritis. 160 adults who already used a thumb splint were assigned to do specific exercises. Researchers measured changes in pinch strength and pain after 1…

This study tested an 8-week dynamic stability exercise program for people with thumb osteoarthritis. 21 adults did exercises at home and in clinic visits. Researchers measured joint alignment with CAT scans and ultrasound to see if the exercises help reduce pain and disability. T…

This study tested whether injecting oxygen-ozone into the thumb joint, along with wearing a splint, reduces pain and improves hand function in people with thumb osteoarthritis. 43 adults took part. The goal was to see if this combination works better than using a splint alone.

This study tested a device that gently stimulates a nerve in the ear to reduce pain and inflammation in people with a severe form of hand osteoarthritis. 148 participants used either the active device or a sham (fake) device daily for 12 weeks. The goal was to see if the real dev…

This study tested whether a single ultrasound-guided injection of Botox into the thumb joint, combined with a splint, can reduce pain in people with base-of-thumb osteoarthritis. Sixty adults with moderate to severe pain received either Botox or a saline placebo injection. The ma…

This study examines nanofat—a processed form of a person's own fat—to see if it could be used as a cell therapy for rhizarthrosis, a common and painful form of thumb osteoarthritis. Researchers will collect fat samples from healthy volunteers and analyze the cells and sterility i…

This study examined whether arthritis in the hands is linked to more severe arthritis in the knees and hips. Researchers used hand X-rays to assess joint damage in 479 adults aged 40 to 75 with confirmed knee or hip arthritis. The goal was to better understand how arthritis progr…