Thumb arthritis showdown: which surgery wins for pain relief?
NCT ID NCT07583628
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study compares two common surgeries for thumb arthritis: total joint replacement (arthroplasty) and trapeziectomy (removing a small bone). Researchers will analyze data from 1,000 patients aged 45 and older in a Swedish registry, tracking pain, function, and complications for one year. The goal is to see which procedure provides better pain relief and faster recovery.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- surgery (total joint arthroplasty or trapeziectomy)
- What this could lead to
- If one surgery proves clearly better, it could guide surgeons and patients toward the most effective option for thumb arthritis pain and function.
- What could go wrong
- This is an observational study using registry data, not a randomized trial, so hidden factors like surgeon skill or patient choice could skew results. Also, the follow-up is only 12 months, so long-term durability is unknown.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
-
About 1,000 people
The number the study aims to enrol. It can still change while the study runs.
- Started
-
Jan 2011
- Finished
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Dec 2025
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Eligible patients are adults aged ≥45 years with a diagnosis of CMC-1 osteoarthritis (ICD-10 code M18) who have failed non-operative treatment and are scheduled for primary CMC-1 surgery.
- Ages
-
45 years and older
- Sex
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Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: adults aged ≥45 years with a diagnosis of CMC-1 osteoarthritis (ICD-10 code M18) who have failed non-operative treatment and are scheduled for primary CMC-1 surgery. Exclusion Criteria: * Bilateral CMC-1 surgery or other simultaneous hand interventions * Previous CMC-1 surgery on the affected hand * Inflammatory joint disease affecting the hands (e.g., rheumatoid arthritis, systemic lupus erythematosus) * 30% missing baseline (preoperative) variables
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
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