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Could a fat and blood injection save your wrist from surgery?

NCT ID NCT03164122

Disease control Sponsor: Assistance Publique Hopitaux De Marseille Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This early-stage trial tested a new injection for wrist osteoarthritis that combines the patient's own fat (microfat) and platelet-rich plasma (PRP). The goal was to see if this mixture is safe and can reduce pain and improve wrist function, potentially delaying the need for surgery. Only 12 people took part, so results are very preliminary.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
mixture of the patient's own fat (microfat) and platelet-rich plasma
What this could lead to
If it works, this could offer a less invasive, injection-based treatment to delay or avoid wrist surgery for osteoarthritis.
What could go wrong
This is a very early, small trial with only 12 participants, so results may not apply widely. The treatment may not provide lasting pain relief or cartilage repair.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 1/2

Runs two stages together: safety and dose first, then whether the treatment works.

Participants

12 people

The number who actually took part.

Started

May 2017

Finished

Jun 2018

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

20 to 75 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Males and females between 20 and 75 years of age * Symptomatic radio-carpal osteoarthritis diagnosed by arthroscanner resistant to medical treatment and candidate to surgery * BMI ≥ 20 Kg/m² * Written informed consent, signed by patient or legal representative (if patient unable to sign). * HB \> 10g/dl * Negative pregnancy test and efficiency contraception Exclusion Criteria: * \- Thrombocytopenia \< 150 G/L, Thrombocytosis \> 450 G/L, Thrombopathy * TP \< 70%, TCA patient / witness rapport \> 1,20 * Anemia: HB \< 10g/dl * Positive serology VIH1 and 2, Agp24, Ac HCV, Ag HbS, AcHbc, Ac HTLV I and II, TPHA * Treatment by platelet inhibiting agent, aspirin, antivitamin K completed more than 2 weeks before inclusion * Chronic treatment by corticosteroid per os or treatment completed more than 2 weeks before inclusion * Intra articular injection of corticosteroid or hyaluronic acid completed more than 8 weeks before inclusion * NSAI treatment completed more than 2 weeks before inclusion * Fever or recent disease completed more than 1 month before inclusion * Auto immune disease, Inflammatory or microcrystalline Arthritis, Immune deficit * Infectious disease * MRI contraindication: ocular loose bodies, pace maker, neurostimulator, cochlear implant, vascular clips, metallic cardiac val * Anesthesia or surgery contra indication, iodine allergy

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Conditions

The condition(s) this trial relates to.

osteoarthritis osteoarthritis, hand

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Osteoarthritis

Contacts and locations

Locations

  • Assisatnce Publique Hopitaux de Marseille

    Marseille, 13354, France

More trials for these conditions

Other studies related to the condition(s) this trial covers.